Ferroptosis mechanisms involved in neurodegenerative diseases

CO Reichert, FA de Freitas, J Sampaio-Silva… - International journal of …, 2020 - mdpi.com
Ferroptosis is a type of cell death that was described less than a decade ago. It is caused by
the excess of free intracellular iron that leads to lipid (hydro) peroxidation. Iron is essential …

New insights into the role of ferritin in iron homeostasis and neurodegenerative diseases

N Zhang, X Yu, J Xie, H Xu - Molecular neurobiology, 2021 - Springer
Growing evidence has indicated that iron deposition is one of the key factors leading to
neuronal death in the neurodegenerative diseases. Ferritin is a hollow iron storage protein …

Serum ferritin: past, present and future

W Wang, MA Knovich, LG Coffman, FM Torti… - Biochimica et Biophysica …, 2010 - Elsevier
BACKGROUND: Serum ferritin was discovered in the 1930s, and was developed as a
clinical test in the 1970s. Many diseases are associated with iron overload or iron deficiency …

Reactive oxygen species as signals that modulate plant stress responses and programmed cell death

TS Gechev, F Van Breusegem, JM Stone, I Denev… - …, 2006 - Wiley Online Library
Reactive oxygen species (ROS) are known as toxic metabolic products in plants and other
aerobic organisms. An elaborate and highly redundant plant ROS network, composed of …

Ferritins: a family of molecules for iron storage, antioxidation and more

P Arosio, R Ingrassia, P Cavadini - Biochimica et Biophysica Acta (BBA) …, 2009 - Elsevier
Ferritins are characterized by highly conserved three-dimensional structures similar to
spherical shells, designed to accommodate large amounts of iron in a safe, soluble and …

Facing the challenges of Cu, Fe and Zn homeostasis in plants

CM Palmer, ML Guerinot - Nature chemical biology, 2009 - nature.com
Plants have recently moved into the spotlight owing to the growing realization that the world
needs solutions to energy and food production that are sustainable and environmentally …

[HTML][HTML] Reactive oxygen species: re-evaluation of generation, monitoring and role in stress-signaling in phototrophic organisms

FJ Schmitt, G Renger, T Friedrich, VD Kreslavski… - … et Biophysica Acta (BBA …, 2014 - Elsevier
This review provides an overview about recent developments and current knowledge about
monitoring, generation and the functional role of reactive oxygen species (ROS)–H 2 O 2 …

Clostridioides difficile ferrosome organelles combat nutritional immunity

H Pi, R Sun, JR McBride, ARS Kruse… - Nature, 2023 - nature.com
Iron is indispensable for almost all forms of life but toxic at elevated levels,,–. To survive
within their hosts, bacterial pathogens have evolved iron uptake, storage and detoxification …

Iron status in patients with chronic heart failure

EA Jankowska, J Malyszko, H Ardehali… - European heart …, 2013 - academic.oup.com
Aims The changes in iron status occurring during the course of heart failure (HF) and the
underlying pathomechanisms are largely unknown. Hepcidin, the major regulatory protein …

[HTML][HTML] Molecular aspects of Cu, Fe and Zn homeostasis in plants

N Grotz, ML Guerinot - Biochimica et Biophysica Acta (BBA)-Molecular Cell …, 2006 - Elsevier
Proper metal transport and homeostasis are critical for the growth and development of
plants. In order to potentially fortify plants pre-harvest with essential metals in aid of human …