Plant secondary metabolites produced in response to abiotic stresses has potential application in pharmaceutical product development

K Yeshi, D Crayn, E Ritmejerytė, P Wangchuk - Molecules, 2022 - mdpi.com
Plant secondary metabolites (PSMs) are vital for human health and constitute the skeletal
framework of many pharmaceutical drugs. Indeed, more than 25% of the existing drugs …

Ibuprofen: pharmacology, efficacy and safety

KD Rainsford - Inflammopharmacology, 2009 - Springer
Objectives This review attempts to bring together information from a large number of recent
studies on the clinical uses, safety and pharmacological properties of ibuprofen. Ibuprofen is …

[PDF][PDF] Применение нестероидных противовоспалительных препаратов. Клинические рекомендации

ЕЛ Насонов, ЛБ Лазебник, ЮН Беленков - Москва, 2006 - psyphysjorn.ru
На сегодняшний день сохраняется потребность в назначении нестероидных
противовоспалительных препаратов (НПВП) в стоматологической практике …

CONSORT for reporting randomized controlled trials in journal and conference abstracts: explanation and elaboration

S Hopewell, M Clarke, D Moher, E Wager… - PLoS …, 2008 - journals.plos.org
Background Clear, transparent, and sufficiently detailed abstracts of conferences and
journal articles related to randomized controlled trials (RCTs) are important, because …

Efficacy and safety of ibuprofen and acetaminophen in children and adults: a meta-analysis and qualitative review

CA Pierce, B Voss - Annals of Pharmacotherapy, 2010 - journals.sagepub.com
Objective: To evaluate the analgesic and antipyretic efficacy and safety of ibuprofen
compared to acetaminophen in children and adults. Data Sources: Literature searches were …

Endogenous opiates and behavior: 2005

RJ Bodnar, GE Klein - Peptides, 2006 - Elsevier
This paper is the 28th consecutive installment of the annual review of research concerning
the endogenous opioid system, now spanning over a quarter-century of research. It …

Effect of intranasal ketamine vs fentanyl on pain reduction for extremity injuries in children: the PRIME randomized clinical trial

TM Frey, TA Florin, M Caruso, N Zhang, Y Zhang… - JAMA …, 2019 - jamanetwork.com
Importance Timely analgesia is critical for children with injuries presenting to the emergency
department, yet pain control efforts are often inadequate. Intranasal administration of pain …

Working towards an appropriate use of ibuprofen in children: an evidence-based appraisal

M de Martino, A Chiarugi, A Boner, G Montini… - Drugs, 2017 - Springer
Ibuprofen is the most widely used non-steroidal anti-inflammatory drug (NSAID) for the
treatment of inflammation, mild-to-moderate pain and fever in children, and is the only …

Oral administration of morphine versus ibuprofen to manage postfracture pain in children: a randomized trial

N Poonai, G Bhullar, K Lin, A Papini, D Mainprize… - Cmaj, 2014 - Can Med Assoc
Background: Recent warnings from Health Canada regarding codeine for children have led
to increased use of nonsteroidal anti-inflammatory drugs and morphine for common injuries …

Oral non‐steroidal anti‐inflammatory drugs versus other oral analgesic agents for acute soft tissue injury

P Jones, SR Dalziel, R Lamdin… - Cochrane Database …, 2015 - cochranelibrary.com
Background Acute soft tissue injuries are common and costly. The best drug treatment for
such injuries is not certain, although non‐steroidal anti‐inflammatory drugs (NSAIDs) are …