Intermittent hypoxia (IH) has been the subject of considerable research in recent years, and
triggers a bewildering array of both detrimental and beneficial effects in multiple …

As in other neural systems, plasticity is a hallmark of the neural system controlling breathing.
One spinal mechanism of respiratory plasticity is phrenic long‐term facilitation (pLTF) …

Acute intermittent hypoxia [AIH; 3, 5-min episodes; 35–45 mmHg arterial Po2 (PaO2)] elicits
serotonin-dependent phrenic long-term facilitation (pLTF), a form of phrenic motor facilitation …

Inflammation undermines neuroplasticity, including serotonin-dependent phrenic long-term
facilitation (pLTF) following moderate acute intermittent hypoxia (mAIH: 3, 5-min episodes …

In 2006, Peters et al. identified 86 systematic reviews (SRs) of laboratory animal
experiments (LAEs). They found 46 LAE meta-analyses (MAs), often of poor quality. Six of …

Plasticity is a fundamental property of the neural system controlling breathing. One
frequently studied model of respiratory plasticity is long‐term facilitation of phrenic motor …

Phrenic long‐term facilitation (pLTF) is a serotonin (5‐HT)‐dependent augmentation of
phrenic motor output induced by acute intermittent hypoxia (AIH). AIH‐induced pLTF …

Many lung and central nervous system disorders require robust and appropriate
physiological responses to assure adequate breathing. Factors undermining the efficacy of …

Although systemic inflammation occurs in most pathological conditions that challenge the
neural control of breathing, little is known concerning the impact of inflammation on …

Breathing is a vital homeostatic behavior and must be precisely regulated throughout life.
Clinical conditions commonly associated with inflammation, undermine respiratory function …