Infection is a dire complication afflicting every field of orthopaedics and traumatology. If
specific clinical, laboratory and imaging parameters are present, infection is often assumed …

Background Accurate diagnosis of prosthetic joint infection (PJI) enables early and effective
treatment. However, there is currently no gold standard test for microbial detection of PJI and …

Background Periprosthetic joint infection (PJI) is the most serious complication of joint
replacement surgery. Further comorbidities include bedsore, deep vein thrombosis …

Abstract 16S ribosomal RNA (rRNA) gene PCR followed by next-generation sequencing
(NGS) was compared to culture of sonicate fluid derived from total elbow arthroplasty for …

Shotgun-metagenomics may give valuable clinical information beyond the detection of
potential pathogen (s). Identification of antimicrobial resistance (AMR), virulence genes and …

Background: Sonication is very efficacious for the microbiological diagnosis of periprosthetic
joint infection (PJI), but it involves many steps and multiple workplaces and personnel and …

Slow-growing Gram-positive anaerobic bacteria (SGAB) such as Cutibacterium acnes are
increasingly recognized as causative agents of implant-associated infections (IAIs) in …

Aims Fungal and mycobacterial periprosthetic joint infections (PJI) are rare events.
Clinicians are wary of missing these diagnoses, often leading to the routine ordering of …

Clinical metagenomics is actively moving from research to clinical laboratories. It has the
potential to change the microbial diagnosis of infectious diseases, especially when detection …

Enrichment of periprosthetic tissue samples in blood culture bottles (BCBs) for
microbiological diagnosis of periprosthetic joint infections (PJI) is more reliable than the use …