Objectives The liberalisation of cannabis laws, the increasing availability and potency of
cannabis has renewed concern about the risk of psychosis with cannabis. Methods The …

Objective: Cannabis use is increasingly normalized; psychosis is a major adverse health
outcome. We reviewed evidence on cannabis use-related risk factors for psychosis …

Cannabis use peaks in adolescence, and adolescents may be more vulnerable to the neural
effects of cannabis and cannabis-related harms due to ongoing brain development during …

Medications to treat substance use disorders remain suboptimal or, in the case of stimulants
and cannabis, non-existent. Many factors have contributed to this paucity, including the …

Introduction Cannabis is the most widely used regulated substance by youth and adults.
Cannabis use has been associated with psychosocial problems, which have been partly …

With an increasing number of countries and states adopting legislation permitting the use of
cannabis for medical purposes, there is a growing interest among health and research …

The elucidation of synaptic density changes provides valuable insights into the underlying
brain mechanisms of substance use. In preclinical studies, synaptic density markers, like …

Objectives Both sleep and cognition are partially modulated by the endocannabinoid (ECB)
system. Cannabis has been reported to have effects on sleep and cognition. This review …

Background Frontotemporal disorders (FTD) are the consequence of impairment to neurons
in the frontal and temporal lobes of the brain. Also, no definitive treatment has been found for …

Cannabis use disorder (CUD) is associated with adverse mental health effects, as well as
social and cognitive impairment. Given prevalence rates of CUD are increasing, there is …