It has been 50 years since Francis Fontan pioneered the operation that today bears his
name. Initially designed for patients with tricuspid atresia, this procedure is now offered for a …

Background and Purpose: The diverse causes of right-sided heart failure (RHF) include,
among others, primary cardiomyopathies with right ventricular (RV) involvement, RV …

Cardiovascular magnetic resonance (CMR) has taken on an increasingly important role in
the diagnostic evaluation and pre-procedural planning for patients with congenital heart …

The past 60 years have brought remarkable advancements in the diagnosis and treatment of
congenital heart disease (CHD). Early diagnosis and improvements in cardiac surgery and …

Abstract The Society for Cardiovascular Magnetic Resonance (SCMR) last published its
comprehensive expert panel report of clinical indications for CMR in 2004. This new …

Abstract The American College of Cardiology (ACC) collaborated with the American Heart
Association, American Society of Echocardiography, Heart Rhythm Society, International …

Rationale: Hypoplastic left heart syndrome (HLHS) remains a lethal congenital cardiac
defect. Recent studies have suggested that intracoronary administration of autologous …

This article provides expert opinion on the use of cardiovascular magnetic resonance (CMR)
in young patients with congenital heart disease (CHD) and in specific clinical situations. As …

Rationale: Patients with single ventricle physiology are at high risk of mortality resulting from
ventricular dysfunction. The preliminary results of the phase 1 trial showed that cardiosphere …

Agonists of peroxisome proliferator-activated receptor gamma (PPAR-γ) can activate 5′
AMP-activated protein kinase alpha (AMPKα) and exert cardioprotective effects. A previous …