[HTML][HTML] A comprehensive review on invasomal carriers incorporating natural terpenes for augmented transdermal delivery

B Kumar, M Pandey, R Aggarwal, PK Sahoo - Future Journal of …, 2022 - Springer
Background Transdermal drug delivery is one of the most widely used drug administration
routes, which offer several advantages over other routes of drug delivery. The apical layer of …

Physiologically based pharmacokinetic model for older adults and its application in geriatric drug research

X Wu, JEV Sia, M Hai, X Lai, H Li… - Current Drug …, 2023 - ingentaconnect.com
Drug-related adverse events are higher in older patients than in non-older patients,
increasing the risk of medication and reducing compliance. Aging is accompanied by a …

Inhibition of sympathetic activation by delivering calcium channel blockers from a 3D printed scaffold to promote bone defect repair

S Li, Z Li, J Yang, Y Ha, X Zhou… - Advanced Healthcare …, 2022 - Wiley Online Library
Enhancing osteogenesis by promoting neural network reconstruction and neuropeptide
release is considered to be an attractive strategy for repairing of critical size bone defects …

[HTML][HTML] Brain targeting of zolmitriptan via transdermal terpesomes: statistical optimization and in vivo biodistribution study by 99mTc radiolabeling technique

MA Tawfik, MM Eltaweel, AM Fatouh… - Drug Delivery and …, 2023 - Springer
Zolmitriptan (ZT) is a potent second generation triptan, commonly administered to alleviate
migraine attacks. ZT suffers various limitations; massive hepatic first pass metabolism, P-gp …

Tailoring terpesomes and leciplex for the effective ocular conveyance of moxifloxacin hydrochloride (Comparative assessment): in-vitro, ex-vivo, and in-vivo evaluation

R Albash, MM Abdellatif, M Hassan… - International Journal of …, 2021 - Taylor & Francis
Aim To compare the ability of both terpesomes (TPs) and leciplex (LPs) loaded moxifloxacin
hydrochloride (MOX) for enhancing ocular drug conveyance. Methods Two separate 21.31 …

The deleterious effect of xylene-induced ear edema in rats: protective role of dexketoprofen trometamol transdermal invasomes via inhibiting the oxidative stress/NF …

SM Soliman, MH Teaima, KO Rashwan, BM Ali… - International Journal of …, 2023 - Elsevier
Pain and inflammation could have a negative impact on a patient's quality of life and
performance, causing them to sleep less. Dexketoprofen trometamol (DKT) is a water …

Low-frequency versus high-frequency ultrasound-mediated transdermal delivery of agomelatine-loaded invasomes: development, optimization and in-vivo …

MA Tawfik, MI Tadros, MI Mohamed… - International journal …, 2020 - Taylor & Francis
Aim Agomelatine (AGM) is the first melatonergic antidepressant. It suffers from low oral
bioavailability (< 5%) due to extensive hepatic metabolism. The current work aimed to …

Augmented Transdermal Delivery of Curcumin for the Effective Management of Plaque Psoriasis – Design, Formulation, Characterisation, and In Vivo Studies

B Kumar, PK Sahoo - AAPS PharmSciTech, 2023 - Springer
Psoriasis is a recurrent, life-threatening anti-inflammatory condition that affects nearly 1–3%
of the global population. It is an autoimmune illness distinguished by hyperplasia of skin …

Integration of terpesomes loaded Levocetrizine dihydrochloride gel as a repurposed cure for Methicillin-Resistant Staphylococcus aureus (MRSA)-Induced skin …

MM El-Naggar, MA El-Nabarawi, MH Teaima… - International Journal of …, 2023 - Elsevier
The intention of this work is to assess the repurposed antimicrobial impact of Levocetirizine
dihydrochloride (LVC), which is a well-known antihistaminic drug, in addition, to augment …

Low-frequency sonophoresis as an active approach to potentiate the transdermal delivery of agomelatine-loaded novasomes: design, optimization, and …

MA Tawfik, MI Mohamed, MI Tadros, SN El-Helaly - AAPS PharmSciTech, 2021 - Springer
The first melatonergic antidepressant drug, agomelatine (AGM), is commonly used for
controlling major depressive disorders. AGM suffers low (< 5%) oral bioavailability owing to …