Antifungal resistance in dermatophytes: Recent trends and therapeutic implications

A Khurana, K Sardana, A Chowdhary - Fungal Genetics and Biology, 2019 - Elsevier
Dermatophytoses or tinea refers to superficial fungal infection of keratinized tissues.
Although generally considered easy to treat, recalcitrant infections, presenting as extensive …

Major challenges and perspectives in the diagnostics and treatment of dermatophyte infections

S Gnat, D Łagowski… - Journal of applied …, 2020 - academic.oup.com
Dermatophytes are the aetiological factors of a majority of superficial fungal infections. What
distinguishes them from other pathogenic filamentous fungi is their unique ability to degrade …

State-of-the-art dermatophyte infections: epidemiology aspects, pathophysiology, and resistance mechanisms

NM Martinez-Rossi, NTA Peres, TA Bitencourt… - Journal of Fungi, 2021 - mdpi.com
The burden of fungal infections is not widely appreciated. Although these infections are
responsible for over one million deaths annually, it is estimated that one billion people are …

Molecular Epidemiology and Antifungal Susceptibility of Trichophyton Isolates in Greece: Emergence of Terbinafine-Resistant Trichophyton mentagrophytes Type …

M Siopi, I Efstathiou, K Theodoropoulos, S Pournaras… - Journal of Fungi, 2021 - mdpi.com
Trichophyton isolates with reduced susceptibility to antifungals are now increasingly
reported worldwide. We therefore studied the molecular epidemiology and the in vitro …

[HTML][HTML] Synthetic antimicrobial peptides: From choice of the best sequences to action mechanisms

PFN Souza, LSM Marques, JTA Oliveira, PG Lima… - Biochimie, 2020 - Elsevier
The emergence of antibiotic-resistant microbes has stimulated research worldwide seeking
new biologically active molecules. In this respect, synthetic antimicrobial peptides (SAMPs) …

The Emerging Terbinafine-Resistant Trichophyton Epidemic: What Is the Role of Antifungal Susceptibility Testing?

JJ Shen, MC Arendrup, S Verma, DML Saunte - Dermatology, 2022 - karger.com
Background: Dermatophytosis is commonly encountered in the dermatological clinics. The
main aetiological agents in dermatophytosis of skin and nails in humans are Trichophyton …

A review on antifungal efficiency of plant extracts entrenched polysaccharide-based nanohydrogels

N Kaur, A Bains, R Kaushik, SB Dhull, F Melinda… - Nutrients, 2021 - mdpi.com
Human skin acts as a physical barrier; however, sometimes the skin gets infected by fungi,
which becomes more severe if the infection occurs on the third layer of the skin. Azole …

Antimicrobials and resistance part II: Antifungals, antivirals, and antiparasitics

FF Muhaj, SJ George, CD Nguyen, SK Tyring - Journal of the American …, 2022 - Elsevier
The available antifungal armamentarium consists of only a few drug classes, many limited in
their use by significant toxicities and dangerous drug interactions. Rising opportunistic …

Natural oils enhance the topical delivery of ketoconazole by nanoemulgel for fungal infections

I Ahmad, M Farheen, A Kukreti, O Afzal, MH Akhter… - ACS …, 2023 - ACS Publications
Nanoemulgel (NEG) pharmaceutical formulations are gaining popularity because of their
ability to serve both as a nanoemulsion and as a gel. These products are well-known for …

The unprecedented epidemic-like scenario of dermatophytosis in India: III. Antifungal resistance and treatment options

SB Verma, S Panda, P Nenoff, A Singal… - Indian Journal of …, 2021 - ijdvl.com
One of the canonical features of the current outbreak of dermatophytosis in India is its
unresponsiveness to treatment in majority of cases. Though there appears to be …