Biological sequence classification: A review on data and general methods

C Ao, S Jiao, Y Wang, L Yu, Q Zou - Research, 2022 - spj.science.org
With the rapid development of biotechnology, the number of biological sequences has
grown exponentially. The continuous expansion of biological sequence data promotes the …

Progresses in predicting post-translational modification

KC Chou - International Journal of Peptide Research and …, 2020 - Springer
Identification of the sites of post-translational modifications (PTMs) in protein, RNA, and DNA
sequences is currently a very hot topic. This is because the information thus obtained is very …

Attention-based multi-label neural networks for integrated prediction and interpretation of twelve widely occurring RNA modifications

Z Song, D Huang, B Song, K Chen, Y Song… - Nature …, 2021 - nature.com
Recent studies suggest that epi-transcriptome regulation via post-transcriptional RNA
modifications is vital for all RNA types. Precise identification of RNA modification sites is …

DeePromoter: robust promoter predictor using deep learning

M Oubounyt, Z Louadi, H Tayara, KT Chong - Frontiers in genetics, 2019 - frontiersin.org
The promoter region is located near the transcription start sites and regulates transcription
initiation of the gene by controlling the binding of RNA polymerase. Thus, promoter region …

H2Opred: a robust and efficient hybrid deep learning model for predicting 2'-O-methylation sites in human RNA

NT Pham, R Rakkiyapan, J Park, A Malik… - Briefings in …, 2024 - academic.oup.com
O-methylation (2OM) is the most common post-transcriptional modification of RNA. It plays a
crucial role in RNA splicing, RNA stability and innate immunity. Despite advances in high …

iHBP-DeepPSSM: Identifying hormone binding proteins using PsePSSM based evolutionary features and deep learning approach

S Akbar, S Khan, F Ali, M Hayat, M Qasim… - … and Intelligent Laboratory …, 2020 - Elsevier
Hormone binding proteins (HBPs) are soluble carrier proteins that can non-covalently and
selectively interact with the human hormone. HBPs plays a significant role in human life, but …

NmRF: identification of multispecies RNA 2'-O-methylation modification sites from RNA sequences

C Ao, Q Zou, L Yu - Briefings in bioinformatics, 2022 - academic.oup.com
O-methylation (Nm) is a post-transcriptional modification of RNA that is catalyzed by 2'-O-
methyltransferase and involves replacing the H on the 2′-hydroxyl group with a methyl …

iN6-Methyl (5-step): Identifying RNA N6-methyladenosine sites using deep learning mode via Chou's 5-step rules and Chou's general PseKNC

I Nazari, M Tahir, H Tayara, KT Chong - Chemometrics and Intelligent …, 2019 - Elsevier
Abstract N6-methyladenosine (m 6 A) is an RNA methylation modification and it is involved
in various biological progresses such as translation, alternative splicing, degradation …

MsDBP: exploring DNA-binding proteins by integrating multiscale sequence information via Chou's five-step rule

X Du, Y Diao, H Liu, S Li - Journal of Proteome Research, 2019 - ACS Publications
DNA-binding proteins are crucial to alternative splicing, methylation, and the structural
composition of the DNA. The existing experimental methods for identifying DNA-binding …

iDNA6mA (5-step rule): Identification of DNA N6-methyladenine sites in the rice genome by intelligent computational model via Chou's 5-step rule

M Tahir, H Tayara, KT Chong - Chemometrics and Intelligent Laboratory …, 2019 - Elsevier
DNA methylation is an elementary epigenetic process. The N6-methyladenine is related to a
large kind of biological processes ie, transcription, DNA replication, and repair. In genome …