Biology of human papillomaviruses
Human papillomaviruses (HPVs) cause squamous cancers of epithelial surfaces, of which
genital cancers are the most common. In this article we have attempted to describe the …
genital cancers are the most common. In this article we have attempted to describe the …
Large T antigens of polyomaviruses: amazing molecular machines
P An, MT Sáenz Robles, JM Pipas - Annual review of …, 2012 - annualreviews.org
The large tumor antigen (T antigen) encoded by simian virus 40 is an amazing molecular
machine because it orchestrates viral infection by modulating multiple fundamental viral and …
machine because it orchestrates viral infection by modulating multiple fundamental viral and …
ARID1A, a Factor That Promotes Formation of SWI/SNF-Mediated Chromatin Remodeling, Is a Tumor Suppressor in Gynecologic Cancers
Abstract ARID1A (BAF250A) promotes the formation of SWI/SNF chromatin remodeling
complexes containing BRG1 or BRM. It has emerged as a candidate tumor suppressor …
complexes containing BRG1 or BRM. It has emerged as a candidate tumor suppressor …
HCV NS5A interacts with p53 and inhibits p53-mediated apoptosis
KH Lan, ML Sheu, SJ Hwang, SH Yen, SY Chen… - Oncogene, 2002 - nature.com
Hepatitis C virus (HCV) causes a persistent infection, chronic hepatitis and hepatocellular
carcinoma. HCV NS5A, one of non-structural proteins of HCV, was suggested to play a role …
carcinoma. HCV NS5A, one of non-structural proteins of HCV, was suggested to play a role …
Oncogenic transformation by BK virus and association with human tumors
BK virus (BKV), a human polyomavirus closely related to JC virus and Simian Virus 40, is
ubiquitous in human populations worldwide. After primary infection, BKV establishes a …
ubiquitous in human populations worldwide. After primary infection, BKV establishes a …
Update on human polyomaviruses and cancer
Over 50 years of polyomavirus research has produced a wealth of insights into not only
general biologic processes in mammalian cells, but also, how conditions can be altered and …
general biologic processes in mammalian cells, but also, how conditions can be altered and …
Hepatitis C virus core protein enhances p53 function through augmentation of DNA binding affinity and transcriptional ability
M Otsuka, N Kato, KH Lan, H Yoshida, J Kato… - Journal of Biological …, 2000 - ASBMB
Hepatitis C virus (HCV) causes a persistent infection, chronic hepatitis, and hepatocellular
carcinoma. Since there are several reports indicating that some viruses influence the tumor …
carcinoma. Since there are several reports indicating that some viruses influence the tumor …
Modulation of p53 transcription regulatory activity and post-translational modification by hepatitis C virus core protein
CF Kao, SY Chen, JY Chen, YH Wu Lee - Oncogene, 2004 - nature.com
Oncogenic virus proteins often target to tumor suppressor p53 during virus life cycle. In the
case of hepatitis C virus (HCV) core protein, it has been shown to affect p53-dependent …
case of hepatitis C virus (HCV) core protein, it has been shown to affect p53-dependent …
SV40 large T antigen functions in DNA replication and transformation
DT Simmons - 2000 - Elsevier
Publisher Summary The virally coded large tumor (T) antigen is a multifunctional protein with
amazing versatility. It is involved in an impressive collection of activities that enable the virus …
amazing versatility. It is involved in an impressive collection of activities that enable the virus …
NS3 protein of Hepatitis C virus associates with the tumour suppressor p53 and inhibits its function in an NS3 sequence-dependent manner
L Deng, M Nagano-Fujii, M Tanaka… - Journal of general …, 2006 - microbiologyresearch.org
The N-terminal 198 residues of NS3 (NS3-N) of Hepatitis C virus (HCV) subtype 1b obtained
from 29 patients, as well as full-length NS3 (NS3-Full), were analysed for their subcellular …
from 29 patients, as well as full-length NS3 (NS3-Full), were analysed for their subcellular …