[HTML][HTML] Targeting the ATP synthase in bacterial and fungal pathogens: beyond Mycobacterium tuberculosis

M Vestergaard, D Bald, H Ingmer - Journal of Global Antimicrobial …, 2022 - Elsevier
The ATP synthase is a multicomponent enzyme that is largely conserved across the
kingdoms of life. In many species the ATP synthase is central in the synthesis of ATP by …

[HTML][HTML] Duchenne muscular dystrophy is associated with the inhibition of calcium uniport in mitochondria and an increased sensitivity of the organelles to the calcium …

MV Dubinin, EY Talanov, KS Tenkov… - … et Biophysica Acta (BBA …, 2020 - Elsevier
Duchenne muscular dystrophy (DMD) is characterized by a pronounced and progressive
degradation of the structure of skeletal muscles, which decreases their strength and lowers …

Understanding and exploiting the effect of tuberculosis antimicrobials on host mitochondrial function and bioenergetics

C Cahill, JJ Phelan, J Keane - Frontiers in Cellular and Infection …, 2020 - frontiersin.org
Almost 140 years after its discovery, tuberculosis remains the leading infectious cause of
death globally. For half a century, patients with drug-sensitive and drug-resistant …

[HTML][HTML] Transport of Ca2+ and Ca2+-dependent permeability transition in heart mitochondria in the early stages of Duchenne muscular dystrophy

MV Dubinin, EY Talanov, KS Tenkov… - … et Biophysica Acta (BBA …, 2020 - Elsevier
Duchenne muscular dystrophy (DMD) is a progressive skeletal muscle disease that is
associated with severe cardiac complications in the late stages. Significant mitochondrial …

Itaconic acid impairs the mitochondrial function by the inhibition of complexes II and IV and induction of the permeability transition pore opening in rat liver …

KN Belosludtsev, NV Belosludtseva, EA Kosareva… - Biochimie, 2020 - Elsevier
Itaconic acid (methylene-succinic acid, ItA) is an unsaturated dicarboxylic acid that is
secreted by mammalian macrophages in response to a pro-inflammatory stimulus and …

[HTML][HTML] Effect of betulin and betulonic acid on isolated rat liver mitochondria and liposomes

MV Dubinin, AA Semenova, AI Ilzorkina… - … et Biophysica Acta (BBA …, 2020 - Elsevier
The paper considers the effects of plant triterpenoid betulin and its derivative betulonic acid
on rat liver mitochondria and liposomes. It was found that betulonic acid and, to a lesser …

Transport of Ca2+ and Ca2+-Dependent Permeability Transition in Rat Liver Mitochondria under the Streptozotocin-Induced Type I Diabetes

KN Belosludtsev, EY Talanov, VS Starinets… - Cells, 2019 - mdpi.com
Although diabetes mellitus is known to be a disease associated with mitochondrial
dysfunction, not everything is clear about mitochondrial Ca2+ transport and Ca2+-induced …

Comparison of cyclosporin variants B–E based on their structural properties and activity in mitochondrial membranes

SV Efimov, MV Dubinin, PP Kobchikova… - Biochemical and …, 2020 - Elsevier
Abstract Cyclosporins B, C, D, and E were characterized by NMR spectroscopy, and
backbone flexibility was studied by molecular dynamics simulation. Structures of the …

Препараты для краткосрочной химиотерапии лекарственно-устойчивого туберкулеза и их влияние на организм человека

ГН Можокина, АГ Самойлова… - … и болезни легких, 2022 - tibl-journal.com
Аннотация В обзоре представлены актуальные данные из 88 источников литературы,
касающиеся краткосрочных схем лечения туберкулеза с множественной …

The effect of S-15176 difumarate salt on ultrastructure and functions of liver mitochondria of c57bl/6 mice with streptozotocin/high-fat diet-induced type 2 diabetes

NV Belosludtseva, VS Starinets, LL Pavlik, IB Mikheeva… - Biology, 2020 - mdpi.com
Simple Summary Type II diabetes mellitus (T2DM) is one of the most common diseases,
which currently represents a major medical and social problem due to the chronic course …