Cardiovascular (CV) disease and cancer are the leading causes of death., Over the last
decades, it has been appreciated that both CV disease and cancer are more common in …

Cancer is a major health issue worldwide, and the global burden of cancer is expected to
increase in the coming years. Whereas the limited success with current therapies has driven …

Prostate cancer is a common malignancy in men and the worldwide burden of this disease
is rising. Lifestyle modifications such as smoking cessation, exercise, and weight control …

Emerging evidence supports that cancer incidence is increased in patients with
cardiovascular (CV) disease and heart failure (HF), and patients with HF frequently die from …

Background: Cancer has become a major disease endangering human health around the
world. Conventional chemotherapy suffers from many side effects including pain …

The outcome of tumors results from genetic and epigenetic modifications of the transformed
cells and also from the interactions of the malignant cells with their tumor microenvironment …

Highlights•De novo anticancer drug discovery is challenging and repurposing in oncology is
a promising field.•Drug repositioning increasingly emerges as faster, cheaper and …

A significant amount of research indicates that the cyclooxygenase/prostaglandin E2 (PGE2)
pathway of inflammation contributes to the development and progression of a variety of …

Malignant tumors, another name for cancerous diseases, are a serious public health
concern that not only causes patients to suffer excruciating pain, but also place a significant …

Background Preclinical, epidemiological, and randomised data indicate that aspirin might
prevent tumour development and metastasis, leading to reduced cancer mortality …