The interplay between gut microbiota and Parkinson's disease: Implications on diagnosis and treatment

A Varesi, LIM Campagnoli, F Fahmideh… - International journal of …, 2022 - mdpi.com
The bidirectional interaction between the gut microbiota (GM) and the Central Nervous
System, the so-called gut microbiota brain axis (GMBA), deeply affects brain function and …

Gastrointestinal dysfunction in Parkinson's disease: current and potential therapeutics

MN Han, DI Finkelstein, RM McQuade… - Journal of Personalized …, 2022 - mdpi.com
Abnormalities in the gastrointestinal (GI) tract of Parkinson's disease (PD) sufferers were first
reported over 200 years ago; however, the extent and role of GI dysfunction in PD disease …

Pharmacological treatments for gastroparesis

M Camilleri, KJ Jencks - Pharmacological Reviews, 2024 - Elsevier
Gastroparesis is a neurogastrointestinal disorder of motility in which patients experience
symptoms of nausea, vomiting, bloating, early satiety, postprandial fullness, upper …

Management of dysphagia and gastroparesis in Parkinson's disease in real-world clinical practice–Balancing pharmacological and non-pharmacological approaches

R Bhidayasiri, W Phuenpathom, AH Tan… - Frontiers in Aging …, 2022 - frontiersin.org
Gastrointestinal (GI) issues are commonly experienced by patients with Parkinson's disease
(PD). Those that affect the lower GI tract, such as constipation, are the most frequently …

Iron dysregulation and inflammagens related to oral and gut health are central to the development of Parkinson's disease

MJ Vuuren, TA Nell, JA Carr, DB Kell, E Pretorius - Biomolecules, 2020 - mdpi.com
Neuronal lesions in Parkinson's disease (PD) are commonly associated with α-synuclein (α-
Syn)-induced cell damage that are present both in the central and peripheral nervous …

The gut-brain-microbiome axis and its link to autism: emerging insights and the potential of zebrafish models

DM James, EA Davidson, J Yanes… - Frontiers in cell and …, 2021 - frontiersin.org
Research involving autism spectrum disorder (ASD) most frequently focuses on its key
diagnostic criteria: restricted interests and repetitive behaviors, altered sensory perception …

Severity of dysphagia is associated with hospitalizations and mortality in patients with Parkinson's disease

S Dilmaghani, J Atieh, L Khanna… - …, 2022 - Wiley Online Library
Background Aspiration pneumonia is the commonest cause of hospitalizations and death in
patients with Parkinson's disease (PD). Among these patients, the relationships between …

The substantia nigra modulates proximal colon tone and motility in a vagally‐dependent manner in the rat

T Xing, G Nanni, CR Burkholder… - The Journal of …, 2023 - Wiley Online Library
A monosynaptic pathway connects the substantia nigra pars compacta (SNpc) to neurons of
the dorsal motor nucleus of the vagus (DMV). This monosynaptic pathway modulates the …

Gastrointestinal dysfunction in genetically defined neurodevelopmental disorders

EA Davidson, C Holingue… - Seminars in …, 2023 - thieme-connect.com
Gastrointestinal symptoms are common in most forms of neurodevelopment disorders
(NDDs) such as in autism spectrum disorders (ASD). The current patient-reported outcome …

[HTML][HTML] Probiotic Influences on Motor Skills: A Review

R Lalonde, C Strazielle - Current Neuropharmacology, 2023 - ncbi.nlm.nih.gov
The effects of probiotics have mostly been shown to be favorable on measures of anxiety
and stress. More recent experiments indicate single-and multi-strain probiotics in treating …