Metabolic syndrome
SL Samson, AJ Garber - Endocrinology and Metabolism Clinics, 2014 - endo.theclinics.com
A medical syndrome is a clustering of clinical findings that occur together more often than
would be expected by chance. The constellation of components that make up the metabolic …
would be expected by chance. The constellation of components that make up the metabolic …
Mechanisms of obesity-induced inflammation and insulin resistance: insights into the emerging role of nutritional strategies
MA McArdle, OM Finucane, RM Connaughton… - Frontiers in …, 2013 - frontiersin.org
Obesity and associated chronic inflammation initiate a state of insulin resistance (IR). The
secretion of chemoattractants such as MCP-1 and MIF and of cytokines IL-6, TNF-α, and IL …
secretion of chemoattractants such as MCP-1 and MIF and of cytokines IL-6, TNF-α, and IL …
Role of immune cells in obesity induced low grade inflammation and insulin resistance
A Asghar, N Sheikh - Cellular immunology, 2017 - Elsevier
The frequency of obesity is enormously growing worldwide. Obesity results when energy
intake exceeds, energy expenditure. Excess adiposity is a major risk factor in the progress of …
intake exceeds, energy expenditure. Excess adiposity is a major risk factor in the progress of …
Fat cell size: measurement methods, pathophysiological origins, and relationships with metabolic dysregulations
The obesity pandemic increasingly causes morbidity and mortality from type 2 diabetes,
cardiovascular diseases and many other chronic diseases. Fat cell size (FCS) predicts …
cardiovascular diseases and many other chronic diseases. Fat cell size (FCS) predicts …
Metabolically healthy obesity: definitions, determinants and clinical implications
CM Phillips - Reviews in Endocrine and Metabolic Disorders, 2013 - Springer
Obesity is associated with increased risk of developing metabolic syndrome (MetS), type 2
diabetes mellitus (T2DM) and cardiovascular disease (CVD) leading to higher all-cause …
diabetes mellitus (T2DM) and cardiovascular disease (CVD) leading to higher all-cause …
Does inflammation determine metabolic health status in obese and nonobese adults?
CM Phillips, IJ Perry - The Journal of Clinical Endocrinology & …, 2013 - academic.oup.com
Context: Inflammation is a potential mechanism linking obesity and cardiometabolic risk.
Limited data on inflammatory markers in metabolically healthy obese and nonobese …
Limited data on inflammatory markers in metabolically healthy obese and nonobese …
Metabolically healthy obesity across the life course: epidemiology, determinants, and implications
CM Phillips - Annals of the New York Academy of Sciences, 2017 - Wiley Online Library
In recent years, different subphenotypes of obesity have been described, including
metabolically healthy obesity (MHO), in which a proportion of obese individuals, despite …
metabolically healthy obesity (MHO), in which a proportion of obese individuals, despite …
Adipose tissue hypoxia, inflammation, and fibrosis in obese insulin-sensitive and obese insulin-resistant subjects
HM Lawler, CM Underkofler, PA Kern… - The Journal of …, 2016 - academic.oup.com
Context: A substantial number of obese individuals are relatively insulin sensitive and the
etiology for this variation remains unknown. Objective: The primary objective was to detect …
etiology for this variation remains unknown. Objective: The primary objective was to detect …
'Metabolically healthy obesity': origins and implications
GV Denis, MS Obin - Molecular aspects of medicine, 2013 - Elsevier
When humans eat more and exercise less, they tend to become obese and unhealthy. The
molecular pathways that link obesity to serious diseases like Type 2 diabetes and …
molecular pathways that link obesity to serious diseases like Type 2 diabetes and …
Metabolically healthy obesity—heterogeneity in definitions and unconventional factors
I Brandão, MJ Martins, R Monteiro - Metabolites, 2020 - mdpi.com
The concept of heterogeneity among obese individuals in their risk for developing metabolic
dysfunction and associated complications has been recognized for decades. At the origin of …
dysfunction and associated complications has been recognized for decades. At the origin of …