A medical syndrome is a clustering of clinical findings that occur together more often than
would be expected by chance. The constellation of components that make up the metabolic …

Obesity and associated chronic inflammation initiate a state of insulin resistance (IR). The
secretion of chemoattractants such as MCP-1 and MIF and of cytokines IL-6, TNF-α, and IL …

The frequency of obesity is enormously growing worldwide. Obesity results when energy
intake exceeds, energy expenditure. Excess adiposity is a major risk factor in the progress of …

The obesity pandemic increasingly causes morbidity and mortality from type 2 diabetes,
cardiovascular diseases and many other chronic diseases. Fat cell size (FCS) predicts …

Obesity is associated with increased risk of developing metabolic syndrome (MetS), type 2
diabetes mellitus (T2DM) and cardiovascular disease (CVD) leading to higher all-cause …

Context: Inflammation is a potential mechanism linking obesity and cardiometabolic risk.
Limited data on inflammatory markers in metabolically healthy obese and nonobese …

In recent years, different subphenotypes of obesity have been described, including
metabolically healthy obesity (MHO), in which a proportion of obese individuals, despite …

Context: A substantial number of obese individuals are relatively insulin sensitive and the
etiology for this variation remains unknown. Objective: The primary objective was to detect …

When humans eat more and exercise less, they tend to become obese and unhealthy. The
molecular pathways that link obesity to serious diseases like Type 2 diabetes and …

The concept of heterogeneity among obese individuals in their risk for developing metabolic
dysfunction and associated complications has been recognized for decades. At the origin of …