Unraveling the mysteries of serum albumin—more than just a serum protein

AM Merlot, DS Kalinowski, DR Richardson - Frontiers in physiology, 2014 - frontiersin.org
Serum albumin is a multi-functional protein that is able to bind and transport numerous
endogenous and exogenous compounds. The development of albumin drug carriers is …

Capping gold nanoparticles with albumin to improve their biomedical properties

K Bolaños, MJ Kogan, E Araya - International journal of …, 2019 - Taylor & Francis
Nanotechnology is an emerging field which has created great opportunities either through
the creation of new materials or by improving the properties of existing ones. Nanoscale …

Albumin tailoring fluorescence and photothermal conversion effect of near-infrared-II fluorophore with aggregation-induced emission characteristics

S Gao, G Wei, S Zhang, B Zheng, J Xu, G Chen… - Nature …, 2019 - nature.com
Fluorophores with donor-acceptor-donor groups with the emission spanning the second
near-infrared window (NIR-II) have recently received great attention for biomedical …

Impact of albumin on drug delivery—New applications on the horizon

B Elsadek, F Kratz - Journal of Controlled Release, 2012 - Elsevier
Over the past decades, albumin has emerged as a versatile carrier for therapeutic and
diagnostic agents, primarily for diagnosing and treating diabetes, cancer, rheumatoid …

nab-Paclitaxel mechanisms of action and delivery

DA Yardley - Journal of Controlled Release, 2013 - Elsevier
Taxanes are a key chemotherapy component for several malignancies, including metastatic
breast cancer (MBC), ovarian cancer, and advanced non-small cell lung cancer (NSCLC) …

Interactions of nanomaterials and biological systems: Implications to personalized nanomedicine

XQ Zhang, X Xu, N Bertrand, E Pridgen… - Advanced drug delivery …, 2012 - Elsevier
The application of nanotechnology to personalized medicine provides an unprecedented
opportunity to improve the treatment of many diseases. Nanomaterials offer several …

Extracellular matrix molecules: potential targets in pharmacotherapy

H Järveläinen, A Sainio, M Koulu, TN Wight… - Pharmacological …, 2009 - ASPET
The extracellular matrix (ECM) consists of numerous macromolecules classified traditionally
into collagens, elastin, and microfibrillar proteins, proteoglycans including hyaluronan, and …

A clinical update of using albumin as a drug vehicle—A commentary

F Kratz - Journal of controlled release, 2014 - Elsevier
Human serum albumin (HSA) has emerged as a versatile carrier for therapeutic agents,
primarily for treating diabetes and cancer, improving the pharmacokinetic profile of the drug …

Clinical impact of serum proteins on drug delivery

F Kratz, B Elsadek - Journal of Controlled Release, 2012 - Elsevier
Among serum proteins albumin and transferrin have attracted the most interest as drug
carriers in the past two decades. Prior to that, their potential use was overshadowed by the …

The endothelial cell tube formation assay on basement membrane turns 20: state of the science and the art

I Arnaoutova, J George, HK Kleinman, G Benton - Angiogenesis, 2009 - Springer
It has been more than 20 years since it was first demonstrated that endothelial cells will
rapidly form capillary-like structures in vitro when plated on top of a reconstituted basement …