Unraveling the mysteries of serum albumin—more than just a serum protein
AM Merlot, DS Kalinowski, DR Richardson - Frontiers in physiology, 2014 - frontiersin.org
Serum albumin is a multi-functional protein that is able to bind and transport numerous
endogenous and exogenous compounds. The development of albumin drug carriers is …
endogenous and exogenous compounds. The development of albumin drug carriers is …
Capping gold nanoparticles with albumin to improve their biomedical properties
Nanotechnology is an emerging field which has created great opportunities either through
the creation of new materials or by improving the properties of existing ones. Nanoscale …
the creation of new materials or by improving the properties of existing ones. Nanoscale …
Albumin tailoring fluorescence and photothermal conversion effect of near-infrared-II fluorophore with aggregation-induced emission characteristics
Fluorophores with donor-acceptor-donor groups with the emission spanning the second
near-infrared window (NIR-II) have recently received great attention for biomedical …
near-infrared window (NIR-II) have recently received great attention for biomedical …
Impact of albumin on drug delivery—New applications on the horizon
B Elsadek, F Kratz - Journal of Controlled Release, 2012 - Elsevier
Over the past decades, albumin has emerged as a versatile carrier for therapeutic and
diagnostic agents, primarily for diagnosing and treating diabetes, cancer, rheumatoid …
diagnostic agents, primarily for diagnosing and treating diabetes, cancer, rheumatoid …
nab-Paclitaxel mechanisms of action and delivery
DA Yardley - Journal of Controlled Release, 2013 - Elsevier
Taxanes are a key chemotherapy component for several malignancies, including metastatic
breast cancer (MBC), ovarian cancer, and advanced non-small cell lung cancer (NSCLC) …
breast cancer (MBC), ovarian cancer, and advanced non-small cell lung cancer (NSCLC) …
Interactions of nanomaterials and biological systems: Implications to personalized nanomedicine
XQ Zhang, X Xu, N Bertrand, E Pridgen… - Advanced drug delivery …, 2012 - Elsevier
The application of nanotechnology to personalized medicine provides an unprecedented
opportunity to improve the treatment of many diseases. Nanomaterials offer several …
opportunity to improve the treatment of many diseases. Nanomaterials offer several …
Extracellular matrix molecules: potential targets in pharmacotherapy
H Järveläinen, A Sainio, M Koulu, TN Wight… - Pharmacological …, 2009 - ASPET
The extracellular matrix (ECM) consists of numerous macromolecules classified traditionally
into collagens, elastin, and microfibrillar proteins, proteoglycans including hyaluronan, and …
into collagens, elastin, and microfibrillar proteins, proteoglycans including hyaluronan, and …
A clinical update of using albumin as a drug vehicle—A commentary
F Kratz - Journal of controlled release, 2014 - Elsevier
Human serum albumin (HSA) has emerged as a versatile carrier for therapeutic agents,
primarily for treating diabetes and cancer, improving the pharmacokinetic profile of the drug …
primarily for treating diabetes and cancer, improving the pharmacokinetic profile of the drug …
Clinical impact of serum proteins on drug delivery
F Kratz, B Elsadek - Journal of Controlled Release, 2012 - Elsevier
Among serum proteins albumin and transferrin have attracted the most interest as drug
carriers in the past two decades. Prior to that, their potential use was overshadowed by the …
carriers in the past two decades. Prior to that, their potential use was overshadowed by the …
The endothelial cell tube formation assay on basement membrane turns 20: state of the science and the art
I Arnaoutova, J George, HK Kleinman, G Benton - Angiogenesis, 2009 - Springer
It has been more than 20 years since it was first demonstrated that endothelial cells will
rapidly form capillary-like structures in vitro when plated on top of a reconstituted basement …
rapidly form capillary-like structures in vitro when plated on top of a reconstituted basement …