[HTML][HTML] A blood–brain barrier overview on structure, function, impairment, and biomarkers of integrity

H Kadry, B Noorani, L Cucullo - Fluids and Barriers of the CNS, 2020 - Springer
The blood–brain barrier is playing a critical role in controlling the influx and efflux of
biological substances essential for the brain's metabolic activity as well as neuronal function …

Chaos and commotion in the wake of cortical spreading depression and spreading depolarizations

D Pietrobon, MA Moskowitz - Nature Reviews Neuroscience, 2014 - nature.com
Punctuated episodes of spreading depolarizations erupt in the brain, encumbering tissue
structure and function, and raising fascinating unanswered questions concerning their …

Serum S100β: A noninvasive marker of blood‐brain barrier function and brain lesions

AA Kanner, N Marchi, V Fazio… - … Journal of the …, 2003 - Wiley Online Library
BACKGROUND S100β protein is expressed constitutively by brain astrocytes. Elevated
S100β levels in cerebrospinal fluid and serum reported after head trauma, subarachnoid …

Anatomy of the brain neurogenic zones revisited: fractones and the fibroblast/macrophage network

F Mercier, JT Kitasako, GI Hatton - Journal of Comparative …, 2002 - Wiley Online Library
Cytogenesis in adult peripheral organs, and in all organs during development, occurs
nearby basal laminae (BL) overlying connective tissue. Paradoxically, cytogenesis in the …

Serum S-100β as a possible marker of blood–brain barrier disruption

M Kapural, LJ Krizanac-Bengez, G Barnett, J Perl… - Brain research, 2002 - Elsevier
Two brain-specific proteins, S-100β and neuron-specific enolase (NSE), are released
systemically after cerebral lesions, but S-100β levels sometimes rise in the absence of …

[HTML][HTML] Parenchymal neuroinflammatory signaling and dural neurogenic inflammation in migraine

ŞE Erdener, Z Kaya, T Dalkara - The journal of headache and pain, 2021 - Springer
Background Pain is generally concomitant with an inflammatory reaction at the site where
the nociceptive fibers are activated. Rodent studies suggest that a sterile meningeal …

Peripheral markers of blood–brain barrier damage

N Marchi, M Cavaglia, V Fazio, S Bhudia, K Hallene… - Clinica chimica acta, 2004 - Elsevier
Neurological diseases are often associated with cerebrovascular dysfunction and changes
in blood–brain barrier (BBB) function. This is important for two seemingly conflicting reasons …

Peripheral markers of brain damage and blood-brain barrier dysfunction

N Marchi, P Rasmussen, M Kapural… - Restorative …, 2003 - content.iospress.com
Purpose: Occurrence of brain damage is frequently associated with abnormal blood-brain
barrier (BBB) function. Two brain-specific proteins, S100β and neuron-specific enolase …

Novel extracellular matrix structures in the neural stem cell niche capture the neurogenic factor fibroblast growth factor 2 from the extracellular milieu

A Kerever, J Schnack, D Vellinga, N Ichikawa… - Stem …, 2007 - academic.oup.com
The novel extracellular matrix structures called fractones are found in the lateral ventricle
walls, the principal adult brain stem cell niche. By electron microscopy, fractones were …

[HTML][HTML] Meninges: from protective membrane to stem cell niche

I Decimo, G Fumagalli, V Berton… - American journal of …, 2012 - ncbi.nlm.nih.gov
Meninges are a three tissue membrane primarily known as coverings of the brain. More in
depth studies on meningeal function and ultrastructure have recently changed the view of …