Autoimmune encephalitis: clinical spectrum and management

CE Uy, S Binks, SR Irani - Practical neurology, 2021 - pn.bmj.com
Autoimmune encephalitis defines brain inflammation caused by a misdirected immune
response against self-antigens expressed in the central nervous system. It comprises a …

Autoimmune encephalitis: proposed recommendations for symptomatic and long-term management

H Abboud, J Probasco, SR Irani, B Ances… - Journal of Neurology …, 2021 - jnnp.bmj.com
The objective of this paper is to evaluate available evidence for each step in autoimmune
encephalitis management and provide expert opinion when evidence is lacking. The paper …

Use and safety of immunotherapeutic management of N-methyl-d-aspartate receptor antibody encephalitis: a meta-analysis

M Nosadini, M Eyre, E Molteni, T Thomas… - JAMA …, 2021 - jamanetwork.com
Importance Overall, immunotherapy has been shown to improve outcomes and reduce
relapses in individuals withN-methyl-d-aspartate receptor (NMDAR) antibody encephalitis …

International consensus recommendations for the treatment of pediatric NMDAR antibody encephalitis

M Nosadini, T Thomas, M Eyre, B Anlar… - Neurology …, 2021 - AAN Enterprises
Objective To create an international consensus treatment recommendation for pediatric
NMDA receptor antibody encephalitis (NMDARE). Methods After selection of a panel of 27 …

Seronegative autoimmune encephalitis: clinical characteristics and factors associated with outcomes

WJ Lee, HS Lee, DY Kim, HS Lee, J Moon, KI Park… - Brain, 2022 - academic.oup.com
Seronegative autoimmune encephalitis is autoimmune encephalitis without any identifiable
pathogenic antibody. Although it is a major subtype of autoimmune encephalitis, many …

Development of the clinical assessment scale in autoimmune encephalitis

JA Lim, ST Lee, J Moon, JS Jun, TJ Kim… - Annals of …, 2019 - Wiley Online Library
Objective There is no scale for rating the severity of autoimmune encephalitis (AE). In this
study, we aimed to develop a novel scale for rating severity in patients with diverse AE …

Systematic review: syndromes, early diagnosis, and treatment in autoimmune encephalitis

C Hermetter, F Fazekas, S Hochmeister - Frontiers in neurology, 2018 - frontiersin.org
In recent years, new antibodies have been discovered which mediate autoimmune
encephalitis. This immunological response can be triggered by an infection or a tumor …

Unconventional T cells in brain homeostasis, injury and neurodegeneration

M Lv, Z Zhang, Y Cui - Frontiers in Immunology, 2023 - frontiersin.org
The interaction between peripheral immune cells and the brain is an important component of
the neuroimmune axis. Unconventional T cells, which include natural killer T (NKT) cells …

[HTML][HTML] Teratoma removal, steroid, IVIG, rituximab and tocilizumab (T-SIRT) in anti-NMDAR encephalitis

WJ Lee, ST Lee, YW Shin, HS Lee, HR Shin, DY Kim… - …, 2021 - Elsevier
In anti-N-methyl-d-aspartate receptor (NMDAR) encephalitis, we analysed the efficacy of a
combined immunotherapy protocol consisting of teratoma removal, steroid, intravenous …

Innate immunity in the central nervous system: a missing piece of the autoimmune encephalitis puzzle?

R Wesselingh, H Butzkueven, K Buzzard… - Frontiers in …, 2019 - frontiersin.org
The autoimmune encephalitides are a group of autoimmune conditions targeting the central
nervous system and causing severe clinical symptoms including drug-resistant seizures …