[HTML][HTML] Traumatic brain injury: progress and challenges in prevention, clinical care, and research
Executive summary Traumatic brain injury (TBI) has the highest incidence of all common
neurological disorders, and poses a substantial public health burden. TBI is increasingly …
neurological disorders, and poses a substantial public health burden. TBI is increasingly …
Neuroinflammatory pathways as treatment targets and biomarkers in epilepsy
A Vezzani, S Balosso, T Ravizza - Nature Reviews Neurology, 2019 - nature.com
Epilepsy is a chronic neurological disease characterized by an enduring propensity for
generation of seizures. The pathogenic processes of seizure generation and recurrence are …
generation of seizures. The pathogenic processes of seizure generation and recurrence are …
[HTML][HTML] The far-reaching scope of neuroinflammation after traumatic brain injury
DW Simon, MJ McGeachy, H Bayır, RSB Clark… - Nature Reviews …, 2017 - nature.com
The'silent epidemic'of traumatic brain injury (TBI) has been placed in the spotlight as a result
of clinical investigations and popular press coverage of athletes and veterans with single or …
of clinical investigations and popular press coverage of athletes and veterans with single or …
A review of the molecular mechanisms of traumatic brain injury
AA Ladak, SA Enam, MT Ibrahim - World neurosurgery, 2019 - Elsevier
Traumatic brain injury (TBI) refers to any insult to the brain resulting in primary (direct) and
secondary (indirect) damage to the brain parenchyma. Secondary damage is often linked to …
secondary (indirect) damage to the brain parenchyma. Secondary damage is often linked to …
Advances in the development of biomarkers for epilepsy
Over 50 million people worldwide have epilepsy. In nearly 30% of these cases, epilepsy
remains unsatisfactorily controlled despite the availability of over 20 antiepileptic drugs …
remains unsatisfactorily controlled despite the availability of over 20 antiepileptic drugs …
Epileptogenesis
A Pitkänen, K Lukasiuk… - Cold Spring …, 2015 - perspectivesinmedicine.cshlp.org
Epileptogenesis is a chronic process that can be triggered by genetic or acquired factors,
and that can continue long after epilepsy diagnosis. In 2015, epileptogenesis is not a …
and that can continue long after epilepsy diagnosis. In 2015, epileptogenesis is not a …
[HTML][HTML] Inflammation in epileptogenesis after traumatic brain injury
Background Epilepsy is a common and debilitating consequence of traumatic brain injury
(TBI). Seizures contribute to progressive neurodegeneration and poor functional and …
(TBI). Seizures contribute to progressive neurodegeneration and poor functional and …
Traumatic brain injury: integrated approaches to improve prevention, clinical care, and research
Executive summary A concerted effort to tackle the global health problem posed by traumatic
brain injury (TBI) is long overdue. TBI is a public health challenge of vast, but insufficiently …
brain injury (TBI) is long overdue. TBI is a public health challenge of vast, but insufficiently …
[HTML][HTML] Recent advances in epilepsy
M Manford - Journal of neurology, 2017 - Springer
This paper reviews advances in epilepsy in recent years with an emphasis on therapeutics
and underlying mechanisms, including status epilepticus, drug and surgical treatments …
and underlying mechanisms, including status epilepticus, drug and surgical treatments …
Inflammation and reactive oxygen species as disease modifiers in epilepsy
G Terrone, S Balosso, A Pauletti, T Ravizza… - …, 2020 - Elsevier
Neuroinflammation and reactive oxygen and nitrogen species are rapidly induced in the
brain after acute cerebral injuries that are associated with an enhanced risk for epilepsy in …
brain after acute cerebral injuries that are associated with an enhanced risk for epilepsy in …