Background As a major virus outbreak in the 21st century, the Coronavirus disease 2019
(COVID-19) pandemic has led to unprecedented hazards to mental health globally. While …

Stress is a primary risk factor for several neuropsychiatric disorders. Evidence from
preclinical models and clinical studies of depression have revealed an array of structural …

Background With the increase in the aging population worldwide, Alzheimer's disease has
become a rapidly increasing public health concern. Monitoring the dementia disease burden …

Sex differences exist in many neurological and psychiatric diseases, but these have not
always been addressed adequately in research. In order to address this, it is necessary to …

The study of chronic pain continues to generate ever-increasing numbers of publications,
but safe and efficacious treatments for chronic pain remain elusive. Recognition of sex …

Estradiol decline can result in depressive disorders in females; nevertheless, the causes of
this decline are unclear. In this study, we isolated estradiol-degrading Klebsiella aerogenes …

AD is a neurodegenerative disease, and its frequency is often reported to be higher for
women than men: almost two-thirds of patients with AD are women. One prevailing view is …

Depression is a heterogeneous and etiologically complex psychiatric syndrome, not a
unitary disease entity, encompassing a broad spectrum of psychopathology arising from …

Few studies have examined changes in mental health before and after the outbreak of
COVID-19. We examined changes in the prevalence of major depression and generalized …

In the midst of the COVID–19 epidemic, Spain was one of the countries with the highest
number of infections and a high mortality rate. The threat of the virus and consequences of …