Lactation is critical to infant short-term and long-term health and protects mothers from
breast cancer, ovarian cancer and type 2 diabetes mellitus. The mammary gland is a …

Breast cancer is the most commonly diagnosed cancer and second-leading cause of cancer
deaths in women. Breast cancer stem cells (BCSCs) promote metastasis and therapeutic …

Stigmasterol (ST), a phytosterol found in food, has various biological activities. However, the
effect of ST on milk synthesis in dairy cows remains unclear. Therefore, bovine primary …

Calcium plays central roles in numerous biological processes, thereby, its levels in the blood
are under strict control to maintain homeostatic balance and enable the proper functioning of …

Simple Summary Parathyroid-hormone-related protein (PTHrP) is produced in normal breast
and breast cancer cells and causes bone destruction when expressed by cancer cells that …

The role of parathyroid hormone (PTH)-related protein (PTHrP) in breast cancer remains
controversial, with reports of PTHrP inhibiting or promoting primary tumor growth in …

Lactation initiation refers to a functional change in the mammary organ from a non-lactating
state to a lactating state, and a series of cytological changes in the mammary epithelium …

Hypercalcemia, caused by tumor secretion of parathyroid hormone-related protein (PTHrP),
is associated with anorexia and weight loss. We demonstrate that overexpression of PTHrP …

Forkhead box protein A1 (FOXA1), a pioneering transcriptional factor known for its critical
roles in prostate and ERα–positive breast cancer, is also expressed in human epidermal …