[HTML][HTML] Interaction of membrane/lipid rafts with the cytoskeleton: impact on signaling and function: membrane/lipid rafts, mediators of cytoskeletal arrangement and …

BP Head, HH Patel, PA Insel - Biochimica et Biophysica Acta (BBA) …, 2014 - Elsevier
The plasma membrane in eukaryotic cells contains microdomains that are enriched in
certain glycosphingolipids, gangliosides, and sterols (such as cholesterol) to form …

Mechanisms of endocytosis

GJ Doherty, HT McMahon - Annual review of biochemistry, 2009 - annualreviews.org
Endocytic mechanisms control the lipid and protein composition of the plasma membrane,
thereby regulating how cells interact with their environments. Here, we review what is known …

Using evolutionary data to make sense of macromolecules with a “face‐lifted” ConSurf

B Yariv, E Yariv, A Kessel, G Masrati, AB Chorin… - Protein …, 2023 - Wiley Online Library
The ConSurf web‐sever for the analysis of proteins, RNA, and DNA provides a quick and
accurate estimate of the per‐site evolutionary rate among homologues. The analysis reveals …

Molecular architecture of the human caveolin-1 complex

JC Porta, B Han, A Gulsevin, JM Chung, Y Peskova… - Science …, 2022 - science.org
Membrane-sculpting proteins shape the morphology of cell membranes and facilitate
remodeling in response to physiological and environmental cues. Complexes of the …

Signaling mechanisms regulating endothelial permeability

D Mehta, AB Malik - Physiological reviews, 2006 - journals.physiology.org
The microvascular endothelial cell monolayer localized at the critical interface between the
blood and vessel wall has the vital functions of regulating tissue fluid balance and supplying …

Role of caveolae and caveolins in health and disease

AW Cohen, R Hnasko, W Schubert… - Physiological …, 2004 - journals.physiology.org
Although they were discovered more than 50 years ago, caveolae have remained enigmatic
plasmalemmal organelles. With their characteristic “flasklike” shape and virtually ubiquitous …

Lipid rafts, caveolae, and their endocytosis

P Lajoie, IR Nabi - International review of cell and molecular biology, 2010 - Elsevier
Lipid rafts are plasma membrane microdomains enriched in cholesterol and sphingolipids
that are involved in the lateral compartmentalization of molecules at the cell surface …

Direct effects of sex steroid hormones on adipose tissues and obesity

JS Mayes, GH Watson - Obesity reviews, 2004 - Wiley Online Library
Sex steroid hormones are involved in the metabolism, accumulation and distribution of
adipose tissues. It is now known that oestrogen receptor, progesterone receptor and …

Caveolin-1 in oncogenic transformation, cancer, and metastasis

TM Williams, MP Lisanti - American Journal of Physiology …, 2005 - journals.physiology.org
Caveolae are 50-to 100-nm omega-shaped invaginations of the plasma membrane that
function as regulators of signal transduction. Caveolins are a class of oligomeric structural …

Caveolae as organizers of pharmacologically relevant signal transduction molecules

HH Patel, F Murray, PA Insel - Annu. Rev. Pharmacol. Toxicol., 2008 - annualreviews.org
Caveolae, a subset of membrane (lipid) rafts, are flask-like invaginations of the plasma
membrane that contain caveolin proteins, which serve as organizing centers for cellular …