Impact of aging on immunity in the context of COVID-19, HIV, and tuberculosis

A Grifoni, T Alonzi, G Alter, DMC Noonan… - Frontiers in …, 2023 - frontiersin.org
Knowledge of aging biology needs to be expanded due to the continuously growing number
of elderly people worldwide. Aging induces changes that affect all systems of the body. The …

The importance of measuring SARS-CoV-2-specific T-cell responses in an ongoing pandemic

L Petrone, A Sette, RD de Vries, D Goletti - Pathogens, 2023 - mdpi.com
Neutralizing antibodies are considered a correlate of protection against SARS-CoV-2
infection and severe COVID-19, although they are not the only contributing factor to …

Outcomes with and without outpatient SARS-CoV-2 treatment for patients with COVID-19 and systemic autoimmune rheumatic diseases: a retrospective cohort study

G Qian, X Wang, NJ Patel, Y Kawano, X Fu… - The Lancet …, 2023 - thelancet.com
Background Some patients with systemic autoimmune rheumatic disease and
immunosuppression might still be at risk of severe COVID-19. The effect of outpatient SARS …

Heterologous vector versus homologous mRNA COVID-19 booster vaccination in non-seroconverted immunosuppressed patients: a randomized controlled trial

D Mrak, D Sieghart, E Simader, S Tobudic… - Nature …, 2022 - nature.com
Impaired response to COVID-19 vaccination is of particular concern in immunosuppressed
patients. To determine the best vaccination strategy for this vulnerable group we performed …

Determinants of antibody responses to SARS-CoV-2 vaccines: population-based longitudinal study (COVIDENCE UK)

DA Jolliffe, SE Faustini, H Holt, N Perdek, S Maltby… - Vaccines, 2022 - mdpi.com
Antibody responses to SARS-CoV-2 vaccines vary for reasons that remain poorly
understood. A range of sociodemographic, behavioural, clinical, pharmacologic and …

[HTML][HTML] Booster dose of SARS-CoV-2 messenger RNA vaccines strengthens the specific immune response of patients with rheumatoid arthritis: A prospective …

C Farroni, A Aiello, A Picchianti-Diamanti… - International Journal of …, 2022 - Elsevier
Objectives To characterize the kinetics of humoral and T-cell responses in rheumatoid
arthritis (RA)-patients followed up to 4-6 weeks (T3) after the SARS-CoV-2 vaccine booster …

[HTML][HTML] Accuracy of QuantiFERON SARS-CoV-2 research use only assay and characterization of the CD4+ and CD8+ T cell-SARS-CoV-2 response: comparison with …

A Aiello, A Coppola, V Vanini, L Petrone… - International Journal of …, 2022 - Elsevier
Objectives: In this study, we aimed to characterize the SARS-CoV-2-specific T cell response
detected by the QuantiFERON SARS-CoV-2 research use only assay in terms of accuracy …

The long term vaccine‐induced anti‐SARS‐CoV‐2 immune response is impaired in quantity and quality under TNFα blockade

UM Geisen, R Rose, F Neumann… - Journal of medical …, 2022 - Wiley Online Library
The humoral immune response to severe acute respiratory syndrome coronavirus 2 (SARS‐
CoV‐2) vaccination in patients with chronic inflammatory disease (CID) declines more …

Factors influencing the SARS-CoV-2 infection and vaccination induced immune response in rheumatoid arthritis

D Nemeth, H Vago, L Tothfalusi, Z Ulakcsai… - Frontiers in …, 2022 - frontiersin.org
Background To investigate the factors that have significant impact on the Severe Acute
Respiratory Syndrome Corona Virus 2 (SARS-CoV-2) infection and vaccination induced …

Longitudinal characterisation of B and T-cell immune responses after the booster dose of COVID-19 mRNA-vaccine in people with multiple sclerosis using different …

A Aiello, A Coppola, S Ruggieri, C Farroni… - Journal of Neurology …, 2023 - jnnp.bmj.com
Background The decline of humoral response to COVID-19 vaccine led to authorise a
booster dose. Here, we characterised the kinetics of B-cell and T-cell immune responses in …