[HTML][HTML] Mechanisms of SARS-CoV-2 entry into cells

CB Jackson, M Farzan, B Chen, H Choe - Nature reviews Molecular …, 2022 - nature.com
The unprecedented public health and economic impact of the COVID-19 pandemic caused
by infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has been …

Liquid–liquid phase separation in human health and diseases

B Wang, L Zhang, T Dai, Z Qin, H Lu, L Zhang… - … and Targeted Therapy, 2021 - nature.com
Emerging evidence suggests that liquid–liquid phase separation (LLPS) represents a vital
and ubiquitous phenomenon underlying the formation of membraneless organelles in …

Tools and techniques for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)/COVID-19 detection

SH Safiabadi Tali, JJ LeBlanc, Z Sadiq… - Clinical microbiology …, 2021 - Am Soc Microbiol
SUMMARY The coronavirus disease 2019 (COVID-19) pandemic, caused by severe acute
respiratory disease coronavirus 2 (SARS-CoV-2), has led to millions of confirmed cases and …

[HTML][HTML] Evolution of antibody immunity to SARS-CoV-2

C Gaebler, Z Wang, JCC Lorenzi, F Muecksch, S Finkin… - Nature, 2021 - nature.com
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has infected 78 million
individuals and is responsible for over 1.7 million deaths to date. Infection is associated with …

Nuclear pores dilate and constrict in cellulo

CE Zimmerli, M Allegretti, V Rantos, SK Goetz… - Science, 2021 - science.org
INTRODUCTION The nucleus harbors and protects the genetic information in eukaryotes. It
is surrounded by the nuclear envelope, which separates the nucleoplasm from the cytosol …

Mapping neutralizing and immunodominant sites on the SARS-CoV-2 spike receptor-binding domain by structure-guided high-resolution serology

L Piccoli, YJ Park, MA Tortorici, N Czudnochowski… - Cell, 2020 - cell.com
Analysis of the specificity and kinetics of neutralizing antibodies (nAbs) elicited by SARS-
CoV-2 infection is crucial for understanding immune protection and identifying targets for …

Effect of natural mutations of SARS-CoV-2 on spike structure, conformation, and antigenicity

SMC Gobeil, K Janowska, S McDowell, K Mansouri… - Science, 2021 - science.org
INTRODUCTION Variants of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-
2) have been circulating worldwide since the beginning of the pandemic. Some are termed …

[HTML][HTML] Molecular architecture of the SARS-CoV-2 virus

H Yao, Y Song, Y Chen, N Wu, J Xu, C Sun, J Zhang… - Cell, 2020 - cell.com
SARS-CoV-2 is an enveloped virus responsible for the COVID-19 pandemic. Despite recent
advances in the structural elucidation of SARS-CoV-2 proteins, the detailed architecture of …

Cross-linking mass spectrometry for investigating protein conformations and protein–protein interactions─ a method for all seasons

L Piersimoni, PL Kastritis, C Arlt, A Sinz - Chemical Reviews, 2021 - ACS Publications
Mass spectrometry (MS) has become one of the key technologies of structural biology. In this
review, the contributions of chemical cross-linking combined with mass spectrometry (XL …

TMPRSS2 expression dictates the entry route used by SARS‐CoV‐2 to infect host cells

J Koch, ZM Uckeley, P Doldan, M Stanifer… - The EMBO …, 2021 - embopress.org
SARS‐CoV‐2 is a newly emerged coronavirus that caused the global COVID‐19 outbreak in
early 2020. COVID‐19 is primarily associated with lung injury, but many other clinical …