PEGylated PAMAM dendrimers: Enhancing efficacy and mitigating toxicity for effective anticancer drug and gene delivery
Abstract Poly (amidoamine) dendrimers (PAMAM) are well-defined, highly branched,
nanoscale macromolecules with numerous active amine groups on the surface. PAMAM …
nanoscale macromolecules with numerous active amine groups on the surface. PAMAM …
RGD engineered dendrimer nanotherapeutic as an emerging targeted approach in cancer therapy
A bird's eye view is now demanded in the area of cancer research to suppress the suffering
of cancer patient and mediate the lack of treatment related to chemotherapy. Chemotherapy …
of cancer patient and mediate the lack of treatment related to chemotherapy. Chemotherapy …
Poly (amidoamine)(PAMAM) dendrimer mediated delivery of drug and pDNA/siRNA for cancer therapy
J Li, H Liang, J Liu, Z Wang - International journal of pharmaceutics, 2018 - Elsevier
Abstract Poly (amidoamine)(PAMAM) dendrimers are well-defined, highly branched
macromolecules with numerous active amine groups on the surface. Because of their …
macromolecules with numerous active amine groups on the surface. Because of their …
Dendrimer nanoarchitectures for cancer diagnosis and anticancer drug delivery
Highlights•Dendrimers are efficient nanocarriers having biomedical and diagnostic
application potentials.•Dendrimers can be efficiently encapsulated with drugs by host–guest …
application potentials.•Dendrimers can be efficiently encapsulated with drugs by host–guest …
[PDF][PDF] Recent applications of polyethylene glycols (PEGs) and PEG derivatives
D Hutanu, MD Frishberg, L Guo, CC Darie - Mod. Chem. Appl, 2014 - jenkemusa.com
Numerous applications of polyethylene glycol derived polymers (PEGs) have been reported
in the scientific literature for many years. With increasing experience and comfort by …
in the scientific literature for many years. With increasing experience and comfort by …
[HTML][HTML] Advances in antitumor nano-drug delivery systems of 10-hydroxycamptothecin
Y Chen, Z Wang, X Wang, M Su, F Xu… - International Journal …, 2022 - ncbi.nlm.nih.gov
Hydroxycamptothecin (HCPT) is a natural plant alkaloid from Camptotheca that shows
potent antitumor activity by targeting intracellular topoisomerase I. However, factors such as …
potent antitumor activity by targeting intracellular topoisomerase I. However, factors such as …
Nanodrug formed by coassembly of dual anticancer drugs to inhibit cancer cell drug resistance
Carrier-free pure nanodrugs (PNDs) that are composed entirely of pharmaceutically active
molecules are regarded as promising candidates to be the next generation of drug …
molecules are regarded as promising candidates to be the next generation of drug …
[HTML][HTML] The Influence of pluronic F68 and F127 nanocarrier on physicochemical properties, in vitro release, and antiproliferative activity of thymoquinone drug
Background: This study reports on hydrophobic drug thymoquinone (TQ), an active
compound found in the volatile oil of Nigella sativa that exhibits anticancer activities …
compound found in the volatile oil of Nigella sativa that exhibits anticancer activities …
Functionalized PAMAM constructed nanosystems for biomacromolecule delivery
Polyamidoamines (PAMAMs) are a class of dendrimer with monodispersity and controlled
topology, which can deliver biologically active macromolecules (eg, genes and proteins) to …
topology, which can deliver biologically active macromolecules (eg, genes and proteins) to …
Recent advances in multifunctional dendrimer-based nanoprobes for breast cancer theranostics
Breast cancer (BC) undoubtedly is one of the most common type of cancers amongst
women, which causes about 5 million deaths annually. The treatments and diagnostic …
women, which causes about 5 million deaths annually. The treatments and diagnostic …