Plasma membrane proteomics of human breast cancer cell lines identifies potential targets for breast cancer diagnosis and treatment

YS Ziegler, JJ Moresco, PG Tu, JR Yates III… - PloS one, 2014 - journals.plos.org
The use of broad spectrum chemotherapeutic agents to treat breast cancer results in
substantial and debilitating side effects, necessitating the development of targeted therapies …

Tubulin cofactor A functions as a novel positive regulator of ccRCC progression, invasion and metastasis

P Zhang, X Ma, E Song, W Chen… - … journal of cancer, 2013 - Wiley Online Library
Microtubules (Mts), which consist of α/β‐tubulin heterodimers, are involved in cancer
development and metastasis. Tubulin cofactor A (TBCA) plays crucial roles in modulating …

[HTML][HTML] Expression of ERCC1, RRM1, TUBB3 in correlation with apoptosis repressor ARC, DNA mismatch repair proteins and p53 in liver metastasis of colorectal …

C Tóth, F Sükösd, E Valicsek… - International …, 2017 - spandidos-publications.com
Liver metastasis in colorectal cancer is common and the primary treatment is chemotherapy.
To date, there is no routinely used test in clinical practice to predict the effectiveness of …

Sulforaphane-N-Acetyl-Cysteine inhibited autophagy leading to apoptosis via Hsp70-mediated microtubule disruption

Y Hu, Y Zhou, G Yang, Y Wang, Z Zheng, J Li, Y Yan… - Cancer letters, 2018 - Elsevier
Abstract Sulforaphane-N-acetyl-cysteine (SFN-NAC) is a potential drug to inhibit human non-
small cell lung cancer (NSCLC), but the underlying mechanisms are elusive. Here, we …

[HTML][HTML] Class III β-tubulin in colorectal cancer: tissue distribution and clinical analysis of Chinese patients

X Zhao, C Yue, J Chen, C Tian, D Yang… - … Medical Journal of …, 2016 - ncbi.nlm.nih.gov
Class III β-Tubulin in Colorectal Cancer: Tissue Distribution and Clinical Analysis of Chinese
Patients - PMC Back to Top Skip to main content NIH NLM Logo Access keys NCBI Homepage …

Expression of the apoptosis repressor with caspase recruitment domain (ARC) in liver metastasis of colorectal cancer and its correlation with DNA mismatch repair …

C Tóth, J Meinrath, E Herpel, J Derix, J Fries… - Journal of cancer …, 2016 - Springer
Introduction Apoptotic signaling is one of the most important processes in the measurement
of chemotherapeutic effectiveness. In apoptotic machinery, various pathways and proteins …

Two-dimensional differential in-gel electrophoresis for identification of gastric cancer-specific protein markers

C Wu, Z Luo, X Chen, C Wu, D Yao… - Oncology …, 2009 - spandidos-publications.com
Gastric cancer is the second most common fatal malignancy in the world. Proteomics studies
of clinical tumor samples have led to the identification of specific protein markers of gastric …

Bax/tubulin/epithelial-mesenchymal pathways determine the efficacy of silybin analog HM015k in colorectal cancer cell growth and metastasis

H Amawi, NA Hussein, CR Ashby Jr… - Frontiers in …, 2018 - frontiersin.org
The inhibition of apoptosis, disruption of cellular microtubule dynamics, and over-activation
of the epithelial mesenchymal transition (EMT), are involved in the progression, metastasis …

胃癌及癌旁组织定量比较蛋白质组学研究

罗治文, 谢笑娟, 马桂兰, 呼建文, 刘丽杰… - 中国生物工程 …, 2007 - manu60.magtech.com.cn
为寻找胃癌特异的肿瘤标记物, 用于胃癌临床诊断及药物治疗靶点的选择, 本研究采用荧光差异
显示凝胶电泳(DIGE) 技术分离并筛选Cy3, Cy5 及Cy2 荧光素标记的胃癌及对应癌旁组织差异 …

Expression of stem cell markers Nanog and Nestin in lip squamous cell carcinoma and actinic cheilitis

FM Scotti, VC Mitt, DSC Vieira, MT Biz… - Oral …, 2018 - Wiley Online Library
Cancer stem cell (CSC) proteins have been observed in several lesions and are associated
with tumor beginning, evolution, and resistance to treatment. Objectives To investigate the …