The Endocannabinoid System (ECS) is primarily responsible for maintaining homeostasis, a
balance in internal environment (temperature, mood, and immune system) and energy input …

The endocannabinoid system (ECS) is one of the most crucial systems in the human
organism, exhibiting multi-purpose regulatory character. It is engaged in a vast array of …

The CB 1 receptor represents a promising target for the treatment of several disorders
including pain-related disease states. However, therapeutic applications of Δ 9 …

Since antiquity, Cannabis has provoked enormous intrigue for its potential medicinal
properties as well as for its unique pharmacological effects. The elucidation of its major …

Background & Objective: Cannabis is one of the earliest cultivated plants. Cannabis of
industrial utility and culinary value is generally termed as hemp. Conversely, cannabis that is …

Substance use disorder (SUD) is a major public health crisis worldwide, and effective
treatment options are limited. During the past 2 decades, researchers have investigated the …

The cannabinoid CB1 receptor is a G protein coupled receptor and plays an important role
in many biological processes and physiological functions. A variety of CB1 receptor agonists …

Cannabinoid pharmacology has been intensely studied because of cannabis' pervasive
medicinal and non-medicinal uses as well as for the therapeutic potential of cannabinoid …

Blockade of cannabinoid type 1 (CB 1)-receptor signaling decreases the rewarding
properties of many drugs of abuse and has been proposed as an anti-addiction strategy …

Allosteric modulators of cannabinoid receptors hold great therapeutic potential, as they do
not possess intrinsic efficacy, but instead enhance or diminish the receptor's response of …