[HTML][HTML] NETosis and neutrophil extracellular traps in COVID-19: immunothrombosis and beyond
Y Zhu, X Chen, X Liu - Frontiers in Immunology, 2022 - frontiersin.org
Infection with SARS-CoV-2, the causative agent of the Coronavirus disease 2019 (COVID-
19) pandemic, causes respiratory problems and multifaceted organ dysfunction. A crucial …
19) pandemic, causes respiratory problems and multifaceted organ dysfunction. A crucial …
Neutrophil extracellular traps: from physiology to pathology
At the frontline of the host defence response, neutrophil antimicrobial functions have
adapted to combat infections and injuries of different origins and magnitude. The release of …
adapted to combat infections and injuries of different origins and magnitude. The release of …
Multi-omic profiling reveals widespread dysregulation of innate immunity and hematopoiesis in COVID-19
Our understanding of protective versus pathological immune responses to SARS-CoV-2, the
virus that causes coronavirus disease 2019 (COVID-19), is limited by inadequate profiling of …
virus that causes coronavirus disease 2019 (COVID-19), is limited by inadequate profiling of …
[HTML][HTML] Multivalent glycosystems for human lectins
M Martínez-Bailén, J Rojo… - Chemical Society …, 2023 - pubs.rsc.org
Human lectins are involved in a wide variety of biological processes, both physiological and
pathological, which have attracted the interest of the scientific community working in the …
pathological, which have attracted the interest of the scientific community working in the …
[HTML][HTML] Siglec ligands
A Gonzalez-Gil, RL Schnaar - Cells, 2021 - mdpi.com
A dense and diverse array of glycans on glycoproteins and glycolipids decorate all cell
surfaces. In vertebrates, many of these carry sialic acid, in a variety of linkages and glycan …
surfaces. In vertebrates, many of these carry sialic acid, in a variety of linkages and glycan …
Therapeutic poly (amino acid) s as drug carriers for cancer therapy
As one of the top global health problems, the effective treatment of cancer is one of the most
urgent clinical challenges. Currently, the main treatments for cancer include surgery …
urgent clinical challenges. Currently, the main treatments for cancer include surgery …
[HTML][HTML] Mechanism for the attenuation of neutrophil and complement hyperactivity by MSC exosomes
Complements and neutrophils are two key players of the innate immune system that are
widely implicated as drivers of severe COVID-19 pathogenesis, as evident by the direct …
widely implicated as drivers of severe COVID-19 pathogenesis, as evident by the direct …
Design of Glycopolymers for Controlling the Interactions with Lectins
Carbohydrates are involved in life activities through the interactions with their corresponding
proteins (lectins). Pathogen infection and the regulation of cell activity are controlled by the …
proteins (lectins). Pathogen infection and the regulation of cell activity are controlled by the …
[HTML][HTML] Oxidative stress and ROS-mediated cellular events in RSV infection: potential protective roles of antioxidants
X Yang, X Liu, Y Nie, F Zhan, B Zhu - Virology Journal, 2023 - Springer
Respiratory syncytial virus (RSV), a member of the Pneumoviridae family, can cause severe
acute lower respiratory tract infection in infants, young children, immunocompromised …
acute lower respiratory tract infection in infants, young children, immunocompromised …
The receptor binding domain of SARS-CoV-2 Omicron subvariants targets Siglec-9 to decrease its immunogenicity by preventing macrophage phagocytosis
X He, X Zhang, B Wu, J Deng, Y Zhang, A Zhu… - Nature …, 2024 - nature.com
The development of a vaccine specific to severe acute respiratory syndrome coronavirus 2
Omicron has been hampered due to its low immunogenicity. Here, using reverse …
Omicron has been hampered due to its low immunogenicity. Here, using reverse …