Cytochrome P450 diversity in the tree of life
DR Nelson - Biochimica et Biophysica Acta (BBA)-Proteins and …, 2018 - Elsevier
Sequencing in all areas of the tree of life has produced> 300,000 cytochrome P450 (CYP)
sequences that have been mined and collected. Nomenclature has been assigned to> …
sequences that have been mined and collected. Nomenclature has been assigned to> …
Metabolic diversity and novelties in the oomycetes
HS Judelson - Annual Review of Microbiology, 2017 - annualreviews.org
The eukaryotic microbes called oomycetes include many important saprophytes and
pathogens, with the latter exhibiting necrotrophy, biotrophy, or obligate biotrophy …
pathogens, with the latter exhibiting necrotrophy, biotrophy, or obligate biotrophy …
Fungal P450 monooxygenases - the diversity in catalysis and their promising roles in biocontrol activity
The fungal P 450s catalyze vital monooxygenation reactions in primary and secondary
metabolism, which may lead to the production of diverse secondary metabolites. Many of …
metabolism, which may lead to the production of diverse secondary metabolites. Many of …
Robust Profiling of Cytochrome P450s (P450ome) in Notable Aspergillus spp.
Cytochrome P450s (P450ome) constitute an extended superfamily group of heme-thiolate
enzymes identified in all biological domains. P450omes play a critical role in the oxidation of …
enzymes identified in all biological domains. P450omes play a critical role in the oxidation of …
Molecular evolutionary dynamics of cytochrome P450 monooxygenases across kingdoms: Special focus on mycobacterial P450s
M Parvez, LB Qhanya, NT Mthakathi… - Scientific reports, 2016 - nature.com
Since the initial identification of cytochrome P450 monooxygenases (CYPs/P450s), great
progress has been made in understanding their structure-function relationship, diversity and …
progress has been made in understanding their structure-function relationship, diversity and …
Impact of lifestyle on cytochrome P450 monooxygenase repertoire is clearly evident in the bacterial phylum Firmicutes
T Padayachee, N Nzuza, W Chen, DR Nelson… - Scientific reports, 2020 - nature.com
Abstract Cytochrome P450 monooxygenases (CYPs/P450s), heme thiolate proteins, are
well known for their role in organisms' primary and secondary metabolism. Research on …
well known for their role in organisms' primary and secondary metabolism. Research on …
Genome-wide annotation and comparative analysis of cytochrome P450 monooxygenases in Basidiomycete biotrophic plant pathogens
LB Qhanya, G Matowane, W Chen, Y Sun… - PLoS …, 2015 - journals.plos.org
Fungi are an exceptional source of diverse and novel cytochrome P450 monooxygenases
(P450s), heme-thiolate proteins, with catalytic versatility. Agaricomycotina saprophytes have …
(P450s), heme-thiolate proteins, with catalytic versatility. Agaricomycotina saprophytes have …
More P450s Are Involved in Secondary Metabolite Biosynthesis in Streptomyces Compared to Bacillus, Cyanobacteria, and Mycobacterium
FC Mnguni, T Padayachee, W Chen, D Gront… - International journal of …, 2020 - mdpi.com
Unraveling the role of cytochrome P450 monooxygenases (CYPs/P450s), heme-thiolate
proteins present in living and non-living entities, in secondary metabolite synthesis is …
proteins present in living and non-living entities, in secondary metabolite synthesis is …
Similarities, variations, and evolution of cytochrome P450s in Streptomyces versus Mycobacterium
LM Senate, MP Tjatji, K Pillay, W Chen, NM Zondo… - Scientific reports, 2019 - nature.com
Cytochrome P450 monooxygenases (P450s) found in all domains of life are known for their
catalytic versatility and stereo-and regio-specific activity. While the impact of lifestyle on …
catalytic versatility and stereo-and regio-specific activity. While the impact of lifestyle on …
In Silico Analysis of P450s and Their Role in Secondary Metabolism in the Bacterial Class Gammaproteobacteria
NN Msomi, T Padayachee, N Nzuza, PR Syed, JD Kryś… - Molecules, 2021 - mdpi.com
The impact of lifestyle on shaping the genome content of an organism is a well-known
phenomenon and cytochrome P450 enzymes (CYPs/P450s), heme-thiolate proteins that are …
phenomenon and cytochrome P450 enzymes (CYPs/P450s), heme-thiolate proteins that are …