SUMMARY ANSWER: Pregnant women with hereditary thrombophilia have an increased
risk of RPL, especially for pregnant women with the G1691A mutation of the factor V Leiden …

Recurrent pregnancy loss is a complex health challenge with no universally accepted
definition. Inconsistency in definitions involves not only the number of spontaneous …

Guidelines Committee and the sounding board of BSH. It was also placed on the members
section of the BSH website for comment. It has also been reviewed by Royal College of …

Certain miscarriages result from immunologic factors, but there is no clear identification of
the precise causes of recurrent pregnancy loss (RPL). Miscarriages and RPL can arise from …

Background Thrombophilic gene polymorphism is known to be a risk factor for recurrent
pregnancy loss (RPL), but few studies have confirmed a possible role of thrombophilic …

Studies have indicated that thrombophilic genes polymorphisms are associated with
recurrent pregnancy loss (RPL) in the Iranian population. We aimed to evaluate the precise …

Purpose Numerous studies have investigated the associations between
methylenetetrahydrofolate reductase (MTHFR) gene C677T and A1298C polymorphisms …

Recurrent pregnancy loss (RPL) has become an important reproductive health issue
worldwide. RPL affects about 2%–3% of reproductive-aged women, and makes serious …

Thrombophilia is a generic term that defines an increased propensity toward thrombosis and
associated morbidity. Factor V Leiden (FVL; G1691A) and the prothrombin gene mutation …

Recurrent pregnancy loss (RPL) is a common reproductive problem affecting around 5% of
couples worldwide. At present, about half of RPL cases remained unexplained. Previous …