Astrocytes are a large and diverse population of morphologically complex cells that exist
throughout nervous systems of multiple species. Progress over the last two decades has …

Astrocytes are the most abundant cell type in the central nervous system (CNS), providing
critical roles in the overall maintenance and homeostasis. Over 100 years ago, Cajal first …

The mammalian cerebrum performs high-level sensory perception, motor control and
cognitive functions through highly specialized cortical and subcortical structures. Recent …

The nematode Caenorhabditis elegans is a powerful experimental setting for uncovering
fundamental tenets of nervous system organization and function. Its nearly invariant and …

Astrocytes play essential roles in the neural tissue where they form a continuous network,
while displaying important local heterogeneity. Here, we performed multiclonal lineage …

Cross-talk between peripheral neurons and immune cells is important in pain sensation. We
identified Snx25 as a pain-modulating gene in a transgenic mouse line with reduced pain …

Obesity and aging are two important epidemic factors for metabolic syndrome and many
other health issues, which contribute to devastating diseases such as cardiovascular …

The heterogeneity and molecular characteristics of progenitor cells, especially glial
progenitors, in the developing human cerebral cortex remain elusive. Here, we find that …

The central nervous system is a highly complex network composed of various cell types,
each one with different subpopulations. Each cell type has distinct roles for the functional …

Chronic pain is challenging to treat due to the limited therapeutic options and adverse side-
effects of therapies. Astrocytes are the most abundant glial cells in the central nervous …