Enantiomers, where chirality arises from restricted rotation around a single bond, are
atropisomers. Due to the unique nature of the origins of their chirality, synthetic strategies to …

Axially chiral biaryl scaffolds are vital in natural products, pharmaceuticals, and asymmetric
synthesis. Catalytically atroposelective ring-opening of configurationally labile compounds …

N-heterocyclic carbene (NHC) is a potent organic small-molecule catalyst. However, its high
synthetic price and frequent use in combination with excess oxidants have limited its …

Catalytic asymmetric dynamic kinetic resolution of configurationally labile bridged biaryls is
emerging as a powerful strategy for atropisomer synthesis. However, the reported examples …

In contrast to the well‐established [3+ 2] cycloaddition reactions, the catalytic
enantioselective [3+ n](n≥ 3) cycloaddition reaction of activated isocyanides for the …

Herein, we report an unprecedented strategy for the simultaneous construction of a remote
C–N stereogenic axis and three contiguous stereogenic carbon centers via silver-catalyzed …

The development of catalytic asymmetric reaction with water as the reactant is challenging
due to the reactivity‐and stereoselectivity‐control issues resulted from the low nucleophilicity …

The catalytic reaction of biaryl lactams with activated isocyanides is reported for the first time.
By employing a cooperative catalytic system, oxazole-containing axially chiral biaryl anilines …

We describe herein an intriguing method for the synthesis of biaryl aldehydes bearing both
axial and central chirality through a desymmetric [3+ 2] cycloaddition reaction of activated …

The development of efficient processes for the preparation of structurally diverse axially
chiral biaryls has been an important goal in synthetic organic chemistry and asymmetric …