Insight into Acinetobacter baumannii: pathogenesis, global resistance, mechanisms of resistance, treatment options, and alternative modalities

M Asif, IA Alvi, SU Rehman - Infection and drug resistance, 2018 - Taylor & Francis
Acinetobacter baumannii, once considered a low-category pathogen, has emerged as an
obstinate infectious agent. The scientific community is paying more attention to this …

Tackling threats and future problems of multidrug-resistant bacteria

E Medina, DH Pieper - How to overcome the antibiotic crisis: facts …, 2016 - Springer
With the advent of the antibiotic era, the overuse and inappropriate consumption and
application of antibiotics have driven the rapid emergence of multidrug-resistant pathogens …

Colistin resistance of Acinetobacter baumannii: clinical reports, mechanisms and antimicrobial strategies

Y Cai, D Chai, R Wang, B Liang… - Journal of antimicrobial …, 2012 - academic.oup.com
Colistin is the last resort for treatment of multidrug-resistant Acinetobacter baumannii.
Unfortunately, resistance to colistin has been reported all over the world. The highest …

Colistin and tigecycline resistance in carbapenemase‐producing Gram‐negative bacteria: emerging resistance mechanisms and detection methods

J Osei Sekyere, U Govinden, LA Bester… - Journal of applied …, 2016 - academic.oup.com
A literature review was undertaken to ascertain the molecular basis for tigecycline and
colistin resistance mechanisms and the experimental basis for the detection and delineation …

Combating tigecycline resistant Acinetobacter baumannii: A leap forward towards multi-epitope based vaccine discovery

S Ahmad, KE Ranaghan, SS Azam - European Journal of Pharmaceutical …, 2019 - Elsevier
Global emergence of Tigecycline resistant Acinetobacter baumannii (TRAB) is on the
horizon and poses a very serious threat to human health. There is a pressing demand for …

In Vitro Activity of Tigecycline Against Acinetobacter baumannii: Global Epidemiology and Resistance Mechanisms

S Pournaras, V Koumaki, V Gennimata… - … Infectious Diseases and …, 2016 - Springer
Acinetobacter baumannii is a pathogen of increasing concern, commonly causing outbreaks
in the hospital environment. Of particular concern, A. baumannii strains exhibiting resistance …

Comparative evaluation of tigecycline susceptibility testing methods for expanded-spectrum cephalosporin-and carbapenem-resistant gram-negative pathogens

O Zarkotou, S Pournaras, G Altouvas… - Journal of clinical …, 2012 - Am Soc Microbiol
ABSTRACT We evaluated the Vitek2, Etest, and MIC Test Strip (MTS) methods of tigecycline
susceptibility testing with 241 expanded-spectrum cephalosporin-resistant and/or …

[PDF][PDF] Prevalence of colistin and tigecycline resistance in Acinetobacter baumannii clinical isolates from 2 hospitals in Riyadh Region over a 2-year period

AM Baadani, SI Thawadi, NA El-Khizzi, AS Omrani - Saudi Med J, 2013 - researchgate.net
Objectives: To describe the rates and patterns of colistin and tigecycline resistance among
Acinetobacter baumannii (A. baumannii) isolates from clinical specimens from 2 major …

Plasmid borne Carbapenem-Hydrolyzing Class D β-Lactamases (CHDLs) and AdeABC efflux pump conferring carbapenem-tigecycline resistance among …

M Savari, A Ekrami, S Shoja, A Bahador - Microbial pathogenesis, 2017 - Elsevier
Here we studied the prevalence and mechanisms of simultaneous resistance to
carbapenem and tigecycline and accumulation of resistance determinants reservoirs in …

纸片扩散法与微量肉汤稀释法检测鲍曼不动杆菌对替加环素体外敏感性的比较

潘楚芝, 李裕军, 赵子文, 陈惠玲, 赵祝香, 卢伟波… - 广东医学, 2013 - cqvip.com
目的比较微量肉汤稀释法和纸片扩散法对耐药饱曼不动杆菌替加环素敏感性试验检测结果.
方法收集临床分离的非重复鲍曼不动杆菌42 株, 其中MDR 菌株11 株, XDR 菌株31 株 …