Cancer is one of the most fatal diseases of recent times that causes several deaths every
year. The disease variations in different parts of the world, the impact of available medical …

Cyclic cell-penetrating peptides are relatively a newer class of peptides that have a huge
potential for the intracellular delivery of therapeutic agents aimed at treating challenging …

Although chemotherapy has been known as a powerful medication for cancer treatment over
the years, there is an important necessity for designing a novel targeted drug delivery …

Abstract Cell‐penetrating peptides (CPPs), first identified in HIV a few decades ago,
deserved great attention in the last two decades; especially to support the penetration of …

Cell-impermeable and negatively charged compounds' cellular uptake across the cell
membranes remains challenging. Herein, the synthesis of four linear [(WWRR) 2,(WWRR) …

A new class of peptides, cyclic cell-penetrating peptides (CPPs), has great potential for
delivering a vast variety of therapeutics intracellularly for treating diverse ailments. CPPs …

This review summarizes recent developments in conjugation techniques for the synthesis of
cell-penetrating peptide (CPP)–drug conjugates targeting cancer cells. We will focus on …

Peptide-based drugs are gaining significant momentum in the modern drug discovery, which
is witnessed by the approval of new drugs by the FDA in recent years. On the other hand …

BACKGROUND: Colon cancer is still a crucial concern in the development of
chemotherapeutic drugs due to the drug resistance phenomenon and various side effects to …

The entry of proteins through the cell membrane is challenging, thus limiting their use as
potential therapeutics. Seven cell-penetrating peptides, designed in our laboratory, were …