[HTML][HTML] Effect of high-fat diets on oxidative stress, cellular inflammatory response and cognitive function

BL Tan, ME Norhaizan - Nutrients, 2019 - mdpi.com
Cognitive dysfunction is linked to chronic low-grade inflammatory stress that contributes to
cell-mediated immunity in creating an oxidative environment. Food is a vitally important …

[HTML][HTML] The role of neuroinflammation in postoperative cognitive dysfunction: moving from hypothesis to treatment

SA Safavynia, PA Goldstein - Frontiers in psychiatry, 2019 - frontiersin.org
Postoperative cognitive dysfunction (POCD) is a common complication of the surgical
experience and is common in the elderly and patients with preexisting neurocognitive …

[HTML][HTML] Microglia priming with aging and stress

A Niraula, JF Sheridan, JP Godbout - Neuropsychopharmacology, 2017 - nature.com
The population of aged individuals is increasing worldwide and this has significant health
and socio-economic implications. Clinical and experimental studies on aging have …

[HTML][HTML] Neuroinflammation as the underlying mechanism of postoperative cognitive dysfunction and therapeutic strategies

Z Li, Y Zhu, Y Kang, S Qin, J Chai - Frontiers in cellular neuroscience, 2022 - frontiersin.org
Postoperative cognitive dysfunction (POCD) is a common complication following
surgery/general anesthesia, especially in elderly patients. Severe cases will greatly delay …

[HTML][HTML] The relationship between inflammation and neurocognitive dysfunction in obstructive sleep apnea syndrome

X Liu, Y Ma, R Ouyang, Z Zeng, Z Zhan, H Lu… - Journal of …, 2020 - Springer
Obstructive sleep apnea syndrome (OSAS), a state of sleep disorder, is characterized by
repetitive apnea, chronic hypoxia, oxygen desaturation, and hypercapnia. Previous studies …

Neuroinflammation in the normal aging hippocampus

RM Barrientos, MM Kitt, LR Watkins, SF Maier - Neuroscience, 2015 - Elsevier
A consequence of normal aging is a greater susceptibility to memory impairments following
an immune challenge such as infection, surgery, or traumatic brain injury. The …

High-fat diet and aging interact to produce neuroinflammation and impair hippocampal-and amygdalar-dependent memory

SJ Spencer, H D'Angelo, A Soch, LR Watkins… - Neurobiology of …, 2017 - Elsevier
More Americans are consuming diets higher in saturated fats and refined sugars than ever
before, and based on increasing obesity rates, this is a growing trend among older adults as …

Oxidative stress and mitochondrial dysfunction contributes to postoperative cognitive dysfunction in elderly rats

MB Netto, AN de Oliveira Junior, M Goldim… - Brain, behavior, and …, 2018 - Elsevier
Postoperative cognitive dysfunction (POCD) is defined by cognitive impairment determined
by neuropsychological tests from before to after surgery. Several mechanisms have been …

[HTML][HTML] Biomarkers of postoperative delirium and cognitive dysfunction

A Fournier, R Krause, G Winterer… - Frontiers in aging …, 2015 - frontiersin.org
Elderly surgical patients frequently experience postoperative delirium (POD) and the
subsequent development of postoperative cognitive dysfunction (POCD). Clinical features …

Postoperative cognitive dysfunction: involvement of neuroinflammation and neuronal functioning

IB Hovens, RG Schoemaker, EA van der Zee… - Brain, behavior, and …, 2014 - Elsevier
Postoperative cognitive dysfunction (POCD) has been hypothesized to be mediated by
surgery-induced inflammatory processes, which may influence neuronal functioning either …