Trends in big data analyses by multicenter collaborative translational research in psychiatry
The underlying pathologies of psychiatric disorders, which cause substantial personal and
social losses, remain unknown, and their elucidation is an urgent issue. To clarify the core …
social losses, remain unknown, and their elucidation is an urgent issue. To clarify the core …
Ventral pallidal regulation of motivated behaviors and reinforcement
C Soares-Cunha, JA Heinsbroek - Frontiers in Neural Circuits, 2023 - frontiersin.org
The interconnected nuclei of the ventral basal ganglia have long been identified as key
regulators of motivated behavior, and dysfunction of this circuit is strongly implicated in …
regulators of motivated behavior, and dysfunction of this circuit is strongly implicated in …
Transcriptome profiling of the ventral pallidum reveals a role for pallido-thalamic neurons in cocaine reward
Psychostimulant exposure alters the activity of ventral pallidum (VP) projection neurons.
However, the molecular underpinnings of these circuit dysfunctions are unclear. We used …
However, the molecular underpinnings of these circuit dysfunctions are unclear. We used …
Ventral pallidum neurons dynamically signal relative threat
The ventral pallidum (VP) is anatomically poised to contribute to threat behavior. Recent
studies report a VP population that scales firing increases to reward but decreases firing to …
studies report a VP population that scales firing increases to reward but decreases firing to …
Effects of importin α1/KPNA1 deletion and adolescent social isolation stress on psychiatric disorder-associated behaviors in mice
K Sakurai, T Itou, M Morita, E Kasahara, T Moriyama… - PLoS …, 2021 - journals.plos.org
Importin α1/KPNA1 is a member of the Importin α family widely present in the mammalian
brain and has been characterized as a regulator of neuronal differentiation, synaptic …
brain and has been characterized as a regulator of neuronal differentiation, synaptic …
[HTML][HTML] Neonatal isolation increases the susceptibility to learned helplessness through the aberrant neuronal activity in the ventral pallidum of rats
H Kobayashi, M Fuchikami, K Oga… - Clinical …, 2024 - ncbi.nlm.nih.gov
Objective Environmental deprivation, a type of childhood maltreatment, has been reported to
constrain the cognitive developmental processes such as associative learning and implicit …
constrain the cognitive developmental processes such as associative learning and implicit …
Ventral pallidum neurons signal relative threat
Ventral pallidum (VP) neurons scale firing increases to reward value and decrease firing to
aversive cues. Anatomical connectivity suggests a critical role for the VP in threat-related …
aversive cues. Anatomical connectivity suggests a critical role for the VP in threat-related …
大脳基底核神経回路における腹側淡蒼球の役割解析: 日本生物学的精神医学会での交流から
疋田貴俊 - 日本生物学的精神医学会誌, 2019 - jstage.jst.go.jp
抄録 大脳基底核は意思決定や認知学習において重要な脳部位であり, 精神疾患病態にも大きく
関与している. 日本生物学的精神医学会若手研究者教育プログラムでの交流から …
関与している. 日本生物学的精神医学会若手研究者教育プログラムでの交流から …