The role of miRNAs in laryngeal cancer pathogenesis and therapeutic resistance–A focus on signaling pathways interplay

M Hegazy, MA Elkady, AM Yehia, EGE Elsakka… - … -Research and Practice, 2023 - Elsevier
Laryngeal cancer (LC) is the malignancy of the larynx (voice box). The majority of LC are
squamous cell carcinomas. Many risk factors were reported to be associated with LC as …

Current and future trends on diagnosis and prognosis of glioblastoma: from molecular biology to proteomics

AS Silantyev, L Falzone, M Libra, OI Gurina… - Cells, 2019 - mdpi.com
Glioblastoma multiforme is the most aggressive malignant tumor of the central nervous
system. Due to the absence of effective pharmacological and surgical treatments, the …

Current perspectives in cancer immunotherapy

T Christofi, S Baritaki, L Falzone, M Libra, A Zaravinos - Cancers, 2019 - mdpi.com
Different immunotherapeutic approaches have proved to be of significant clinical value to
many patients with different types of advanced cancer. However, we need more precise …

Association of oral dysbiosis with oral cancer development

GRM La Rosa, G Gattuso, E Pedullà… - Oncology …, 2020 - spandidos-publications.com
Oral squamous cell carcinoma (OSCC) is the leading cause of mortality for oral cancer.
Numerous risk factors mainly related to unhealthy habits and responsible for chronic …

Functional roles of matrix metalloproteinases and their inhibitors in melanoma

S Napoli, C Scuderi, G Gattuso, V Di Bella, S Candido… - Cells, 2020 - mdpi.com
The extracellular matrix (ECM) plays an important role in the regulation of the tissue
microenvironment and in the maintenance of cellular homeostasis. Several proteins with a …

[HTML][HTML] Predicting lncRNA–miRNA interactions based on interactome network and graphlet interaction

L Zhang, T Liu, H Chen, Q Zhao, H Liu - Genomics, 2021 - Elsevier
In the development and treatment of many human diseases, the regulatory roles between
lncRNAs and miRNAs are important, but much remains unknown about them; moreover …

The impact of miRNA in colorectal cancer progression and its liver metastases

O Balacescu, D Sur, C Cainap, S Visan… - International journal of …, 2018 - mdpi.com
Colorectal cancer (CRC) is one of the most commonly diagnosed malignancies with a high
incidence and mortality rate. An essential challenge in colorectal cancer management is to …

Identification of novel MicroRNAs and their diagnostic and prognostic significance in oral cancer

L Falzone, G Lupo, GRM La Rosa, S Crimi, CD Anfuso… - Cancers, 2019 - mdpi.com
Background: Oral cancer is one of the most prevalent cancers worldwide. Despite that the
oral cavity is easily accessible for clinical examinations, oral cancers are often not promptly …

Identification of modulated MicroRNAs associated with breast cancer, diet, and physical activity

L Falzone, M Grimaldi, E Celentano, LSA Augustin… - Cancers, 2020 - mdpi.com
Simple Summary Healthy diet and physical activity are able to induce beneficial molecular
modifications that have been associated with a lower risk of breast cancer (BC) incidence …

The analysis of miRNA expression profiling datasets reveals inverse microRNA patterns in glioblastoma and Alzheimer's disease

S Candido, G Lupo, M Pennisi… - Oncology …, 2019 - spandidos-publications.com
There is recent evidence to indicate the existence of an inverse association between the
incidence of neurological disorders and cancer development. Concurrently, the …