Focus on extracellular vesicles: physiological role and signalling properties of extracellular membrane vesicles
Extracellular vesicles (EVs) are a heterogeneous population of secreted membrane
vesicles, with distinct biogenesis routes, biophysical properties and different functions both …
vesicles, with distinct biogenesis routes, biophysical properties and different functions both …
[HTML][HTML] The stem cell secretome and its role in brain repair
Compelling evidence exists that non-haematopoietic stem cells, including mesenchymal
(MSCs) and neural/progenitor stem cells (NPCs), exert a substantial beneficial and …
(MSCs) and neural/progenitor stem cells (NPCs), exert a substantial beneficial and …
The therapeutic potential of neural stem cells
G Martino, S Pluchino - Nature Reviews Neuroscience, 2006 - nature.com
Recent evidence shows that transplantation of neural stem/precursor cells may protect the
central nervous system from inflammatory damage through a'bystander'mechanism that is …
central nervous system from inflammatory damage through a'bystander'mechanism that is …
Cross-talk between neural stem cells and immune cells: the key to better brain repair?
Systemic or intracerebral delivery of neural stem and progenitor cells (NSPCs) and
activation of endogenous NSPCs hold much promise as potential treatments for diseases in …
activation of endogenous NSPCs hold much promise as potential treatments for diseases in …
Pathophysiology and therapy of experimental stroke
KA Hossmann - Cellular and molecular neurobiology, 2006 - Springer
1. Stroke is the neurological evidence of a critical reduction of cerebral blood flow in a
circumscribed part of the brain, resulting from the sudden or gradually progressing …
circumscribed part of the brain, resulting from the sudden or gradually progressing …
Stem cell‐based therapies for ischemic stroke
L Hao, Z Zou, H Tian, Y Zhang… - BioMed research …, 2014 - Wiley Online Library
In recent years, stem cell‐based approaches have attracted more attention from scientists
and clinicians due to their possible therapeutical effect on stroke. Animal studies have …
and clinicians due to their possible therapeutical effect on stroke. Animal studies have …
Anti-inflammatory mechanism of intravascular neural stem cell transplantation in haemorrhagic stroke
Neural stem cell (NSC) transplantation has been investigated as a means to reconstitute the
damaged brain after stroke. In this study, however, we investigated the effect on acute …
damaged brain after stroke. In this study, however, we investigated the effect on acute …
Neural stem cells transfected with reactive oxygen species–responsive polyplexes for effective treatment of ischemic stroke
Neural stem cells (NSCs), capable of ischemia‐homing, regeneration, and differentiation,
exert strong therapeutic potentials in treating ischemic stroke, but the curative effect is limited …
exert strong therapeutic potentials in treating ischemic stroke, but the curative effect is limited …
Cell transplantation therapy for stroke
T Bliss, R Guzman, M Daadi, GK Steinberg - Stroke, 2007 - Am Heart Assoc
No treatment currently exists to restore lost neurological function after stroke. A growing
number of studies highlight the potential of stem cell transplantation as a novel therapeutic …
number of studies highlight the potential of stem cell transplantation as a novel therapeutic …
A conditionally immortal clonal stem cell line from human cortical neuroepithelium for the treatment of ischemic stroke
K Pollock, P Stroemer, S Patel, L Stevanato… - Experimental …, 2006 - Elsevier
Transplantation of neural stem cells into the brain is a novel approach to the treatment of
chronic stroke disability. For clinical application, safety and efficacy of defined, stable cell …
chronic stroke disability. For clinical application, safety and efficacy of defined, stable cell …