Advances over the past 25 years have revealed much about how the structural properties of
membranes and associated proteins are linked to the thermodynamics and kinetics of …

Cells are constantly submitted to external mechanical stresses, which they must withstand
and respond to. By forming a physical boundary between cells and their environment that is …

Cholesterol/sphingolipid-rich membrane domains, known as lipid rafts or membrane rafts,
play a critical role in the compartmentalization of signaling pathways. Physical segregation …

A number of bacterial cell processes are confined functional membrane microdomains
(FMMs), structurally and functionally similar to lipid rafts of eukaryotic cells. How bacteria …

Despite the ubiquity of transbilayer asymmetry in natural cell membranes, the vast majority
of existing research has utilized chemically well-defined symmetric liposomes, where the …

ABSTRACT Introduction: Extracellular vesicles (EVs) represent an important mode of
intercellular communication. There is now a growing awareness that predominant EV …

Lipid rafts, sites of signal transduction, are enriched in glycosphingolipids (GSLs).
Gangliosides, a class of GSLs found in greatest concentration in the grey matter of the brain …

Ever since technologies enabled the characterization of eukaryotic plasma membranes,
heterogeneities in the distributions of its constituents were observed. Over the years this led …

An interesting concept in the organization of cellular membranes is the proposed existence
of lipid rafts. Membranes of eukaryotic cells organize signal transduction proteins into …

The Brownian motion of molecules at thermal equilibrium usually has a finite correlation time
and will eventually be randomized after a long delay time, so that their displacement follows …