Brain insulin resistance in type 2 diabetes and Alzheimer disease: concepts and conundrums

SE Arnold, Z Arvanitakis… - Nature Reviews …, 2018 - nature.com
Considerable overlap has been identified in the risk factors, comorbidities and putative
pathophysiological mechanisms of Alzheimer disease and related dementias (ADRDs) and …

Impact of diabetes on cognitive function and brain structure

A Moheet, S Mangia… - Annals of the New York …, 2015 - Wiley Online Library
Both type 1 and type 2 diabetes have been associated with reduced performance on
multiple domains of cognitive function and with structural abnormalities in the brain. With an …

[HTML][HTML] Diabetes mellitus and cognitive impairments

E Saedi, MR Gheini, F Faiz, MA Arami - World journal of diabetes, 2016 - ncbi.nlm.nih.gov
There is strong evidence that diabetes mellitus increases the risk of cognitive impairment
and dementia. Insulin signaling dysregulation and small vessel disease in the base of …

Cognitive dysfunction in patients with type 2 diabetes

YD Reijmer, E van den Berg, C Ruis… - Diabetes/metabolism …, 2010 - Wiley Online Library
People with diabetes mellitus are at increased risk of cognitive dysfunction and dementia.
This review explores the nature and severity of cognitive changes in patients with type 2 …

An update on the molecular and cellular basis of pharmacotherapy in type 2 diabetes mellitus

MO Mahgoub, II Ali, JO Adeghate, K Tekes… - International journal of …, 2023 - mdpi.com
Diabetes mellitus (DM) is a chronic illness with an increasing global prevalence. More than
537 million cases of diabetes were reported worldwide in 2021, and the number is steadily …

Type 2 diabetes and cognitive impairment in an older population with overweight or obesity and metabolic syndrome: baseline cross-sectional analysis of the …

N Mallorquí-Bagué, M Lozano-Madrid, E Toledo… - Scientific reports, 2018 - nature.com
This study cross-sectionally examines in the elderly population:(a) the association of type 2
diabetes with executive function (EF);(b) the effect of BMI on both type 2 diabetes and EF;(c) …

A meta-analysis of cognitive functioning in nondemented adults with type 2 diabetes mellitus

MCE Monette, A Baird, DL Jackson - Canadian journal of diabetes, 2014 - Elsevier
Objective The current investigation sought to determine the pattern and magnitude of
cognitive functioning deficits in persons with type 2 diabetes mellitus without dementia using …

Cerebrovascular complications of diabetes: focus on cognitive dysfunction

T Hardigan, R Ward, A Ergul - Clinical Science, 2016 - portlandpress.com
The incidence of diabetes has more than doubled in the United States in the last 30 years
and the global disease rate is projected to double by 2030. Cognitive impairment has been …

Gray matter volume abnormalities in type 2 diabetes mellitus with and without mild cognitive impairment

Y Zhang, X Zhang, J Zhang, C Liu, Q Yuan, X Yin… - Neuroscience …, 2014 - Elsevier
This study sought to evaluate the potential brain gray matter (GM) volume changes that
occur with the transition from normal cognition to mild cognitive impairment (MCI) in patients …

Association between diabetes and cognitive function among people over 45 years old in China: a cross-sectional study

L Zhang, J Yang, Z Liao, X Zhao, X Hu, W Zhu… - International journal of …, 2019 - mdpi.com
Objectives: The aim of this study is to identify the relationship between diabetes status
including characteristics of diabetes and cognition among the middle-aged and elderly …