Review of the endocannabinoid system
The endocannabinoid system (ECS) is a widespread neuromodulatory network involved in
the developing central nervous system as well as playing a major role in tuning many …
the developing central nervous system as well as playing a major role in tuning many …
Goods and bads of the endocannabinoid system as a therapeutic target: Lessons learned after 30 years
The cannabis derivative marijuana is the most widely used recreational drug in the Western
world and is consumed by an estimated 83 million individuals (∼ 3% of the world …
world and is consumed by an estimated 83 million individuals (∼ 3% of the world …
An introduction to the endogenous cannabinoid system
The endocannabinoid system (ECS) is a widespread neuromodulatory system that plays
important roles in central nervous system development, synaptic plasticity, and the response …
important roles in central nervous system development, synaptic plasticity, and the response …
Cardiovascular effects of marijuana and synthetic cannabinoids: the good, the bad, and the ugly
Dysregulation of the endogenous lipid mediators endocannabinoids and their G-protein-
coupled cannabinoid receptors 1 and 2 (CB1R and CB2R) has been implicated in a variety …
coupled cannabinoid receptors 1 and 2 (CB1R and CB2R) has been implicated in a variety …
From phytocannabinoids to cannabinoid receptors and endocannabinoids: pleiotropic physiological and pathological roles through complex pharmacology
A Ligresti, L De Petrocellis… - Physiological …, 2016 - journals.physiology.org
Apart from having been used and misused for at least four millennia for, among others,
recreational and medicinal purposes, the cannabis plant and its most peculiar chemical …
recreational and medicinal purposes, the cannabis plant and its most peculiar chemical …
The endocannabinoid system in guarding against fear, anxiety and stress
The endocannabinoid (eCB) system has emerged as a central integrator linking the
perception of external and internal stimuli to distinct neurophysiological and behavioural …
perception of external and internal stimuli to distinct neurophysiological and behavioural …
The endogenous cannabinoid system: a budding source of targets for treating inflammatory and neuropathic pain
G Donvito, SR Nass, JL Wilkerson, ZA Curry… - …, 2018 - nature.com
A great need exists for the development of new medications to treat pain resulting from
various disease states and types of injury. Given that the endogenous cannabinoid (that is …
various disease states and types of injury. Given that the endogenous cannabinoid (that is …
Endocannabinoids and endocannabinoid-related mediators: Targets, metabolism and role in neurological disorders
FA Iannotti, V Di Marzo, S Petrosino - Progress in lipid research, 2016 - Elsevier
The endocannabinoid system (ECS) is composed of two G protein-coupled receptors
(GPCRs), the cannabinoid CB1 and CB2 receptors, and the two main endogenous lipid …
(GPCRs), the cannabinoid CB1 and CB2 receptors, and the two main endogenous lipid …
Endocannabinoid signaling and synaptic function
Endocannabinoids are key modulators of synaptic function. By activating cannabinoid
receptors expressed in the central nervous system, these lipid messengers can regulate …
receptors expressed in the central nervous system, these lipid messengers can regulate …
Endocannabinoids and related N-acylethanolamines: biological activities and metabolism
K Tsuboi, T Uyama, Y Okamoto, N Ueda - Inflammation and Regeneration, 2018 - Springer
The plant Cannabis sativa contains cannabinoids represented by Δ 9-tetrahydrocannabinol,
which exert psychoactivity and immunomodulation through cannabinoid CB1 and CB2 …
which exert psychoactivity and immunomodulation through cannabinoid CB1 and CB2 …