Raman spectroscopy: techniques and applications in the life sciences

DW Shipp, F Sinjab, I Notingher - Advances in Optics and Photonics, 2017 - opg.optica.org
Raman spectroscopy is an increasingly popular technique in many areas, including biology
and medicine. It is based on Raman scattering, a phenomenon in which incident photons …

Stimulated Raman scattering microscopy: an emerging tool for drug discovery

WJ Tipping, M Lee, A Serrels, VG Brunton… - Chemical Society …, 2016 - pubs.rsc.org
Optical microscopy techniques have emerged as a cornerstone of biomedical research,
capable of probing the cellular functions of a vast range of substrates, whilst being minimally …

Chemically sensitive bioimaging with coherent Raman scattering

CH Camp Jr, MT Cicerone - Nature photonics, 2015 - nature.com
Raman scattering provides an intrinsic fingerprint of chemical composition. Spontaneous
Raman spectroscopy has been used for many decades to interrogate biological materials …

Computational coherent Raman scattering imaging: breaking physical barriers by fusion of advanced instrumentation and data science

H Lin, JX Cheng - eLight, 2023 - Springer
Coherent Raman scattering (CRS) microscopy is a chemical imaging modality that provides
contrast based on intrinsic biomolecular vibrations. To date, endeavors on instrumentation …

Broadband coherent Raman scattering microscopy

D Polli, V Kumar, CM Valensise… - Laser & Photonics …, 2018 - Wiley Online Library
Spontaneous Raman (SR) microscopy allows label‐free chemically specific imaging based
on the vibrational response of molecules; however, due to the low Raman scattering cross …

Direct visualization of de novo lipogenesis in single living cells

J Li, JX Cheng - Scientific reports, 2014 - nature.com
Increased de novo lipogenesis is being increasingly recognized as a hallmark of cancer.
Despite recent advances in fluorescence microscopy, autoradiography and mass …

Review of stimulated Raman scattering microscopy techniques and applications in the biosciences

Y Li, B Shen, S Li, Y Zhao, J Qu, L Liu - Advanced Biology, 2021 - Wiley Online Library
Stimulated Raman scattering (SRS) microscopy is a nonlinear optical imaging method for
visualizing chemical content based on molecular vibrational bonds. Featuring high speed …

Plasmon-enhanced stimulated Raman scattering microscopy with single-molecule detection sensitivity

C Zong, R Premasiri, H Lin, Y Huang, C Zhang… - Nature …, 2019 - nature.com
Stimulated Raman scattering (SRS) microscopy allows for high-speed label-free chemical
imaging of biomedical systems. The imaging sensitivity of SRS microscopy is limited to~ 10 …

Fast vibrational imaging of single cells and tissues by stimulated Raman scattering microscopy

D Zhang, P Wang, MN Slipchenko… - Accounts of chemical …, 2014 - ACS Publications
Conspectus Traditionally, molecules are analyzed in a test tube. Taking biochemistry as an
example, the majority of our knowledge about cellular content comes from analysis of fixed …

SRS-FISH: A high-throughput platform linking microbiome metabolism to identity at the single-cell level

X Ge, FC Pereira, M Mitteregger… - Proceedings of the …, 2022 - National Acad Sciences
One of the biggest challenges in microbiome research in environmental and medical
samples is to better understand functional properties of microbial community members at a …