DNA transfer in forensic science: a review
Understanding the variables impacting DNA transfer, persistence, prevalence and recovery
(DNA-TPPR) has become increasingly relevant in investigations of criminal activities to …
(DNA-TPPR) has become increasingly relevant in investigations of criminal activities to …
Recent trends and developments in forensic DNA extraction
KWY Chong, Z Thong, CKC Syn - … Reviews: Forensic Science, 2021 - Wiley Online Library
The extraction of DNA is a fairly standard procedure routinely undertaken in biological
academic and research settings. In a forensic DNA context, DNA extraction is the crucial first …
academic and research settings. In a forensic DNA context, DNA extraction is the crucial first …
[HTML][HTML] Single-cell transcriptome sequencing allows genetic separation, characterization and identification of individuals in multi-person biological mixtures
L Kulhankova, D Montiel González, E Bindels… - Communications …, 2023 - nature.com
Identifying individuals from biological mixtures to which they contributed is highly relevant in
crime scene investigation and various biomedical research fields, but despite previous …
crime scene investigation and various biomedical research fields, but despite previous …
A systematic approach to improve downstream single‐cell analysis for the DEPArray™ technology
J Schulte, MA Marciano, E Scheurer… - Journal of Forensic …, 2023 - Wiley Online Library
Most commercially available STR amplification kits have never been fully validated for low
template DNA analysis, highlighting the need for testing different PCR kits and conditions for …
template DNA analysis, highlighting the need for testing different PCR kits and conditions for …
[HTML][HTML] Revisiting single cell analysis in forensic science
DRL Watkins, D Myers, HE Xavier, MA Marciano - Scientific Reports, 2021 - nature.com
Forensic science has yet to take full advantage of single cell analysis. Its greatest benefit is
the ability to alleviate the challenges associated with DNA mixture analysis, which remains a …
the ability to alleviate the challenges associated with DNA mixture analysis, which remains a …
Analytical approaches to differential extraction for sexual assault evidence
Many forensic laboratories face growing demands for the processing of DNA evidence from
sexual assault investigations. In these cases, evidence collected from the crime scene or …
sexual assault investigations. In these cases, evidence collected from the crime scene or …
Single cell genomics applications in forensic science: Current state and future directions
K Huffman, J Ballantyne - Iscience, 2023 - cell.com
Standard methods of mixture analysis involve subjecting a dried crime scene sample to
a'bulk'DNA extraction method such that the resulting isolate compromises a homogenized …
a'bulk'DNA extraction method such that the resulting isolate compromises a homogenized …
[HTML][HTML] Pushing the boundaries: forensic DNA phenotyping challenged by single-cell sequencing
M Diepenbroek, B Bayer, K Anslinger - Genes, 2021 - mdpi.com
Single-cell sequencing is a fast developing and very promising field; however, it is not
commonly used in forensics. The main motivation behind introducing this technology into …
commonly used in forensics. The main motivation behind introducing this technology into …
Y‐STR mixture deconvolution by single‐cell analysis
K Huffman, E Hanson… - Journal of Forensic …, 2023 - Wiley Online Library
Since Y‐STR typing only amplifies male Y chromosomal DNA, it can simplify the
interpretation of some DNA mixtures that contain female DNA. However, if there are multiple …
interpretation of some DNA mixtures that contain female DNA. However, if there are multiple …
[HTML][HTML] Optical tweezers as an effective tool for spermatozoa isolation from mixed forensic samples
N Auka, M Valle, BD Cox, PD Wilkerson… - PLoS …, 2019 - journals.plos.org
A single focus optical tweezer is formed when a laser beam is launched through a high
numerical aperture immersion objective. This objective focuses the beam down to a …
numerical aperture immersion objective. This objective focuses the beam down to a …