Duchenne muscular dystrophy (DMD) is caused by the lack of functional dystrophin protein.
Improvements in patient care and disease management have slowed down disease …

Ischemic heart disease is a significant cause of morbidity and mortality in Western society.
Although interventions, such as thrombolysis and percutaneous coronary intervention, have …

Rapamycin has been shown to extend lifespan in numerous model organisms including
mice, with the most dramatic longevity effects reported in females. However, little is known …

Background Muscle wasting and weakness in Duchenne muscular dystrophy (DMD) causes
severe locomotor limitations and early death due in part to respiratory muscle failure. Given …

Duchenne muscular dystrophy (DMD) is the most common form of muscular dystrophy in
childhood. It is caused by mutations of the DMD gene, leading to progressive muscle …

Cardiovascular diseases (CVDs) are the leading causes of mortality worldwide. As a type of
CVDs, myocardial infarction (MI) induces ischemia hypoxia, which leads to excessive …

Introduction Duchenne muscular dystrophy (DMD) is an X-linked recessive disorder caused
by mutations in the dystrophin (DMD) gene. Most patients die from respiratory failure or …

Duchenne muscular dystrophy (DMD) is the most common and severe form of muscular
dystrophy and occurs in 1 in 3500 male births. Improved survival due to improvements in …

Duchenne muscular dystrophy (DMD) is an X-linked myopathy resulting in progressive
weakness and wasting of all the striated muscles including the respiratory muscles. The …

Duchenne muscular dystrophy (DMD) is a fatal neuromuscular disease that affects boys and
leads to early death. In the quest for new treatments that improve the quality of life and in the …