Biomarkers: mining the biofluid proteome
TD Veenstra, TP Conrads, BL Hood, AM Avellino… - Molecular & Cellular …, 2005 - ASBMB
Proteomics has brought with it the hope of identifying novel biomarkers for diseases such as
cancer. This hope is built on the ability of proteomic technologies, such as mass …
cancer. This hope is built on the ability of proteomic technologies, such as mass …
The menagerie of human lipocalins: a natural protein scaffold for molecular recognition of physiological compounds
A Schiefner, A Skerra - Accounts of chemical research, 2015 - ACS Publications
Conspectus While immunoglobulins are well-known for their characteristic ability to bind
macromolecular antigens (ie, as antibodies during an immune response), the lipocalins …
macromolecular antigens (ie, as antibodies during an immune response), the lipocalins …
Suction blister fluid as potential body fluid for biomarker proteins
J Kool, L Reubsaet, F Wesseldijk, RT Maravilha… - …, 2007 - Wiley Online Library
Early diagnosis is important for effective disease management. Measurement of biomarkers
present at the local level of the skin could be advantageous in facilitating the diagnostic …
present at the local level of the skin could be advantageous in facilitating the diagnostic …
Biochemical and Structural Characteristics, Gene Regulation, Physiological, Pathological and Clinical Features of Lipocalin-Type Prostaglandin D2 Synthase as a …
Y Urade - Frontiers in Physiology, 2021 - frontiersin.org
Lipocalin-type prostaglandin (PG) D2 synthase (L-PGDS) catalyzes the isomerization of
PGH2, a common precursor of the two series of PGs, to produce PGD2. PGD2 stimulates …
PGH2, a common precursor of the two series of PGs, to produce PGD2. PGD2 stimulates …
Biomarkers associated with organ-specific involvement in juvenile systemic lupus erythematosus
J Greenan-Barrett, G Doolan, D Shah, S Virdee… - International Journal of …, 2021 - mdpi.com
Juvenile systemic lupus erythematosus (JSLE) is characterised by onset before 18 years of
age and more severe disease phenotype, increased morbidity and mortality compared to …
age and more severe disease phenotype, increased morbidity and mortality compared to …
Lipocalin-type prostaglandin D synthase protects against oxidative stress-induced neuronal cell death
A Fukuhara, M Yamada, K Fujimori… - Biochemical …, 2012 - portlandpress.com
L-PGDS [lipocalin-type PGD (prostaglandin D) synthase] is a dual-functional protein, acting
as a PGD2-producing enzyme and a lipid transporter. L-PGDS is a member of the lipocalin …
as a PGD2-producing enzyme and a lipid transporter. L-PGDS is a member of the lipocalin …
Transferrin isoforms in cerebrospinal fluid and their relation to neurological diseases
Y Murakami, K Saito, H Ito… - Proceedings of the Japan …, 2019 - jstage.jst.go.jp
Iron plays many important roles in the brain, including involvement in myelination,
neurotransmission and electron transfer in the respiratory chain. Transferrin (Tf), an iron …
neurotransmission and electron transfer in the respiratory chain. Transferrin (Tf), an iron …
Rapid, accurate and non-invasive detection of cerebrospinal fluid leakage using combined determination of β-trace protein in secretion and serum
L Risch, I Lisec, M Jutzi, M Podvinec, H Landolt… - Clinica chimica acta, 2005 - Elsevier
BACKGROUND: β-Trace protein (Btp) has been proposed as a valuable marker of
cerebrospinal fluid (CSF) leakage overcoming the drawbacks of β-2-transferrin (B-2Tr) …
cerebrospinal fluid (CSF) leakage overcoming the drawbacks of β-2-transferrin (B-2Tr) …
A unique glycan-isoform of transferrin in cerebrospinal fluid: A potential diagnostic marker for neurological diseases
K Hoshi, Y Matsumoto, H Ito, K Saito, T Honda… - … et Biophysica Acta (BBA …, 2017 - Elsevier
Background Cerebrospinal fluid (CSF) is sequestered from blood by the blood-brain barrier
and directly communicates with brain parenchymal interstitial fluid, leading to contain …
and directly communicates with brain parenchymal interstitial fluid, leading to contain …
Biomarkers in chronic adult hydrocephalus
A Tarnaris, LD Watkins, ND Kitchen - Cerebrospinal fluid research, 2006 - Springer
Awareness of the importance of chronic adult hydrocephalus has been raised again with the
recent emergence of epidemiological studies. It is estimated that between 5 and 10% of …
recent emergence of epidemiological studies. It is estimated that between 5 and 10% of …