A general arene C–H functionalization strategy via electron donor–acceptor complex photoactivation
A Dewanji, L van Dalsen, JA Rossi-Ashton… - Nature Chemistry, 2023 - nature.com
The photoactivation of electron donor–acceptor complexes has emerged as a sustainable,
selective and versatile strategy for the generation of radical species. However, when it …
selective and versatile strategy for the generation of radical species. However, when it …
[HTML][HTML] Interrupted Nef and Meyer reactions: a growing point for diversity-oriented synthesis based on nitro compounds
AY Sukhorukov - Molecules, 2023 - mdpi.com
The Nef reaction (nitro to carbonyl group conversion) and related Meyer reaction are among
the key transformations of aliphatic nitro compounds. The interrupted versions of these …
the key transformations of aliphatic nitro compounds. The interrupted versions of these …
Non-symmetric stapling of native peptides
FJ Chen, W Lin, FE Chen - Nature Reviews Chemistry, 2024 - nature.com
Stapling has emerged as a powerful technique in peptide chemistry. It enables precise
control over peptide conformation leading to enhanced properties such as improved stability …
control over peptide conformation leading to enhanced properties such as improved stability …
Sustainable Claisen-Schmidt chalcone synthesis catalysed by plasma-recovered MgO nanosheets from seawater
UGM Ekanayake, H Weerathunga… - Sustainable Materials …, 2022 - Elsevier
Chalcones enable the biosynthesis of flavonoids which protect plants from infections and
parasites and have emerged as valuable medicines against diverse human diseases. The …
parasites and have emerged as valuable medicines against diverse human diseases. The …
Metal‐Free Arylation of Benzothiophenes at C4 by Activation as their Benzothiophene S‐Oxides
R Bisht, MV Popescu, Z He, AM Ibrahim… - Angewandte Chemie …, 2023 - Wiley Online Library
Benzothiophenes, activated by oxidation to the corresponding S‐oxides, undergo C− H/C−
H‐type coupling with phenols to give C4 arylation products. While an electron‐withdrawing …
H‐type coupling with phenols to give C4 arylation products. While an electron‐withdrawing …
Interrupted Nef reaction of cyclic nitronates: Diastereoselective access to densely substituted α-chloronitroso compounds
RS Malykhin, YD Boyko, YV Nelyubina… - The Journal of …, 2022 - ACS Publications
The reaction of cyclic nitronic esters (isoxazoline-and 5, 6-dihydro-4 H-1, 2-oxazine-N-
oxides) with hydrochloric acid affords geminal chloronitroso compounds bearing a distant …
oxides) with hydrochloric acid affords geminal chloronitroso compounds bearing a distant …
Catalytic asymmetric interrupted Attanasi reaction: access to fused 2, 3-dihydropyrroles with vicinal quaternary carbons
YX Chen, TJ Han, X Xiao, MC Wang… - Chemical …, 2023 - pubs.rsc.org
The first catalytic asymmetric interrupted Attanasi reaction has been established. Under the
catalysis of a bifunctional organocatalyst, the condensation of cyclic β-keto esters with …
catalysis of a bifunctional organocatalyst, the condensation of cyclic β-keto esters with …
Rapid Assembly of Unsymmetrically Linked Bis-heterocycles via Palladium Domino Catalysis
A palladium-catalyzed domino reaction of alkene-tethered oxime esters is reported. This
transformation uses an air-stable palladium precatalyst that initiates a Narasaka–Heck …
transformation uses an air-stable palladium precatalyst that initiates a Narasaka–Heck …
Oxa-Nazarov Cyclization-Michael Addition Sequence for the Rapid Construction of Dihydrofuranones
T Chen, F Gong, S Nagaraju, J Liu, S Yang… - Organic …, 2022 - ACS Publications
The Nazarov cyclization has been established as a powerful tool in constructing
cyclopentenone skeletons. In sharp contrast, oxa-Nazarov cyclization that affords …
cyclopentenone skeletons. In sharp contrast, oxa-Nazarov cyclization that affords …
Each Interruption is an Opportunity: Novel Synthetic Strategies Explored Through Interrupted Click Reactions
F Brunelli, C Russo, M Giustiniano… - Chemistry–A European …, 2024 - Wiley Online Library
The particular and unique mechanism of the copper‐catalyzed reaction between azides and
alkynes (CuAAC) has not only allowed for the efficient synthesis of 1, 2, 3‐trisubstituted 1, 4 …
alkynes (CuAAC) has not only allowed for the efficient synthesis of 1, 2, 3‐trisubstituted 1, 4 …