Immune-mediated inflammatory disease therapeutics: past, present and future

IB McInnes, EM Gravallese - Nature Reviews Immunology, 2021 - nature.com
Immune-mediated inflammatory diseases are common and clinically diverse. Although they
are currently incurable, the therapeutic armamentarium for immune-mediated inflammatory …

Epidemiology of psoriasis and comorbid diseases: a narrative review

J Bu, R Ding, L Zhou, X Chen, E Shen - Frontiers in immunology, 2022 - frontiersin.org
Psoriasis is a chronic autoimmune inflammatory disease that remains active for a long
period, even for life in most patients. The impact of psoriasis on health is not only limited to …

Cohort profile update: the HUNT study, Norway

BO Åsvold, A Langhammer, TA Rehn… - International journal …, 2023 - academic.oup.com
The Trøndelag Health Study (the HUNT Study) is a population-based cohort study of the
adult population in Trøndelag County, Norway. It was previously called the Nord-Trøndelag …

Obesity is a risk factor for severe COVID-19 infection: multiple potential mechanisms

N Sattar, IB McInnes, JJV McMurray - Circulation, 2020 - Am Heart Assoc
Circulation. 2020; 142: 4–6. DOI: 10.1161/CIRCULATIONAHA. 120.047659 July 7, 2020 5
certain ethnicities, eg, Asians. 1 Asians often display lower cardiorespiratory fitness and …

[HTML][HTML] Psoriasis: a brief overview

A Raharja, SK Mahil, JN Barker - Clinical Medicine, 2021 - Elsevier
Psoriasis is a clinically heterogeneous lifelong skin disease that presents in multiple forms
such as plaque, flexural, guttate, pustular or erythrodermic. An estimated 60 million people …

Obesity in COVID-19 era, implications for mechanisms, comorbidities, and prognosis: a review and meta-analysis

SMM Aghili, M Ebrahimpur, B Arjmand… - International journal of …, 2021 - nature.com
Background Recent studies have shown that obesity is associated with the severity of
coronavirus disease (COVID-19). We reviewed clinical studies to clarify the obesity …

Psoriatic arthritis from a mechanistic perspective

G Schett, P Rahman, C Ritchlin, IB McInnes… - Nature Reviews …, 2022 - nature.com
Psoriatic arthritis (PsA) is part of a group of closely related clinical phenotypes ('psoriatic
disease') that is defined by shared molecular pathogenesis resulting in excessive …

Shared genetic risk factors and causal association between psoriasis and coronary artery disease

MT Patrick, Q Li, R Wasikowski, N Mehta… - Nature …, 2022 - nature.com
Psoriasis and coronary artery disease (CAD) are related comorbidities that are well
established, but whether a genetic basis underlies this is not well studied. We apply trans …

[HTML][HTML] The current landscape of psoriasis genetics in 2020

K Ogawa, Y Okada - Journal of dermatological science, 2020 - Elsevier
Psoriasis is an immune-mediated disease associated with skin and joint inflammation that
affects large proportions of populations worldwide. It is a heritable disease: individuals' …

Treating chronic diseases without tackling excess adiposity promotes multimorbidity

N Sattar, JJV McMurray, IB McInnes… - The lancet Diabetes & …, 2023 - thelancet.com
Few people now reach old age without taking multiple drugs, often attending various clinics,
and undergoing secondary or tertiary investigations. Most chronic conditions are, to differing …