Melatonin is uncommonly effective in reducing oxidative stress under a remarkably large
number of circumstances. It achieves this action via a variety of means: direct detoxification …

There is highly credible evidence that melatonin mitigates cancer at the initiation,
progression and metastasis phases. In many cases, the molecular mechanisms …

Oxidative stress (OS) represents a threat to the chemical integrity of biomolecules including
lipids, proteins, and DNA. The associated molecular damage frequently results in serious …

Antioxidant supplements are commonly consumed by endurance athletes to minimize
exercise-induced oxidative stress, with the intention of enhancing recovery and improving …

Osteoarthritis (OA) is a degenerative joint disease characterized by progressive erosion of
articular cartilage. As chondrocytes are the only cell type forming the articular cartilage, their …

Excessive training may limit physiological muscle adaptation through chronic oxidative
stress and inflammation. Improper diet and overtraining may also disrupt intestinal …

Steroid‐induced osteoporosis (SIOP) is a form of secondary osteoporosis, but its specific
mechanism remains unclear. Glucocorticoid (GC‐)‐induced death of osteoblasts and bone …

Melatonin exhibits extraordinary diversity in terms of its functions and distribution. When
discovered, it was thought to be uniquely of pineal gland origin. Subsequently, melatonin …

Skeletal muscle disorders are dramatically increasing with human aging with enormous
sanitary costs and impact on the quality of life. Preventive and therapeutic tools to limit onset …

Background Oxidative stress plays a critical role in pulmonary fibrosis after acute lung injury
(ALI), and epithelial-mesenchymal transition (EMT) events are involved in this process. The …