Idiopathic inflammatory myopathies (IIM), also known as myositis, are a heterogeneous
group of autoimmune disorders with varying clinical manifestations, treatment responses …

The growing field of immunometabolism has taught us how metabolic cellular reactions and
processes not only provide a means to generate ATP and biosynthetic precursors, but are …

Metabolites have functions in the immune system independent of their conventional roles as
sources or intermediates in biosynthesis and bioenergetics. We are still in the pioneering …

Antisynthetase syndrome is an autoimmune condition, characterized by antibodies directed
against an aminoacycl transfer RNA synthetase along with clinical features that can include …

Objective To identify the clinical and laboratory predictors of clinical improvement in a cohort
of myositis patients treated with rituximab. Methods We analyzed data for 195 patients with …

As with the treatment of many immune-mediated diseases, managing myositis encompasses
diverse factors, which present a challenge to the physician caring for these patients. The …

Background: According to widely used criteria (Bohan and Peter criteria, 1975),
dermatomyositis (DM) is differentiated from polymyositis (PM) only by skin changes. More …

Idiopathic inflammatory myopathies (IIMs) are heterogeneous disorders that affect the
skeletal muscles. Polymyositis, dermatomyositis, and inclusion body myositis are major IIM …

Idiopathic inflammatory myopathies (IIM) are a group of chronic, autoimmune conditions
affecting primarily the proximal muscles. The most common types are dermatomyositis (DM) …

Inasmuch as the clinical features of the idiopathic inflammatory myopathies are not easily
differentiated from those of other similar rheumatic and neurologic conditions, diagnosis is …