The gut microbiota (microbiome) in cardiovascular disease and its therapeutic regulation

MM Rahman, F Islam, MH -Or-Rashid… - Frontiers in cellular …, 2022 - frontiersin.org
In the last two decades, considerable interest has been shown in understanding the
development of the gut microbiota and its internal and external effects on the intestine, as …

Gut microbial metabolites in obesity, NAFLD and T2DM

EE Canfora, RCR Meex, K Venema… - Nature Reviews …, 2019 - nature.com
Evidence is accumulating that the gut microbiome is involved in the aetiology of obesity and
obesity-related complications such as nonalcoholic fatty liver disease (NAFLD), insulin …

Role of gut microbiota-generated short-chain fatty acids in metabolic and cardiovascular health

ES Chambers, T Preston, G Frost, DJ Morrison - Current nutrition reports, 2018 - Springer
Abstract Purpose of this Review This review assesses the latest evidence linking short-chain
fatty acids (SCFA) with host metabolic health and cardiovascular disease (CVD) risk and …

Microbial regulation of organismal energy homeostasis

PD Cani, M Van Hul, C Lefort, C Depommier… - Nature …, 2019 - nature.com
The gut microbiome has emerged as a key regulator of host metabolism. Here we review the
various mechanisms through which the gut microbiome influences the energy metabolism of …

Meta-omics analysis of elite athletes identifies a performance-enhancing microbe that functions via lactate metabolism

J Scheiman, JM Luber, TA Chavkin, T MacDonald… - Nature medicine, 2019 - nature.com
The human gut microbiome is linked to many states of human health and disease. The
metabolic repertoire of the gut microbiome is vast, but the health implications of these …

Microbial medicine: prebiotic and probiotic functional foods to target obesity and metabolic syndrome

M Green, K Arora, S Prakash - International journal of molecular sciences, 2020 - mdpi.com
Obesity has become a global epidemic and a public health crisis in the Western World,
experiencing a threefold increase in prevalence since 1975. High-caloric diets and …

Short‐Chain Fatty Acids Ameliorate Diabetic Nephropathy via GPR43‐Mediated Inhibition of Oxidative Stress and NF‐κB Signaling

W Huang, Y Man, C Gao, L Zhou, J Gu… - Oxidative Medicine …, 2020 - Wiley Online Library
Diabetic nephropathy (DN) is a chronic low‐grade inflammatory disease. Oxidative stress
and nuclear factor kappa B (NF‐κB) signaling play an important role in the pathogenesis of …

Contribution of macronutrients to obesity: implications for precision nutrition

R San-Cristobal, S Navas-Carretero… - Nature Reviews …, 2020 - nature.com
The specific metabolic contribution of consuming different energy-yielding macronutrients
(namely, carbohydrates, protein and lipids) to obesity is a matter of active debate. In this …

Dietary macronutrients and the gut microbiome: a precision nutrition approach to improve cardiometabolic health

KM Jardon, EE Canfora, GH Goossens, EE Blaak - Gut, 2022 - gut.bmj.com
Accumulating evidence indicates that the gut microbiome is an important regulator of body
weight, glucose and lipid metabolism, and inflammatory processes, and may thereby play a …

Short chain fatty acids in human gut and metabolic health

EE Blaak, EE Canfora, S Theis, G Frost… - Beneficial …, 2020 - wageningenacademic.com
Evidence is accumulating that short chain fatty acids (SCFA) play an important role in the
maintenance of gut and metabolic health. The SCFA acetate, propionate and butyrate are …