Summary The 2015 Magnetic Resonance Imaging in Multiple Sclerosis and 2016
Consortium of Multiple Sclerosis Centres guidelines on the use of MRI in diagnosis and …

MRI has improved the diagnostic work-up of multiple sclerosis, but inappropriate image
interpretation and application of MRI diagnostic criteria contribute to misdiagnosis. Some …

Recent evidence has shown the existence of a CNS 'waste clearance'system, defined as the
glymphatic system. Glymphatic abnormalities have been described in several …

During the past decades, better understanding of relapsing-remitting multiple sclerosis
disease mechanisms have led to the development of several disease-modifying therapies …

In patients presenting with a clinically isolated syndrome, MRI can support and substitute
clinical information in the diagnosis of multiple sclerosis by showing disease dissemination …

In patients with multiple sclerosis (MS), grey matter damage is widespread and might
underlie many of the clinical symptoms, especially cognitive impairment. This relation …

The clinical use of MRI in patients with multiple sclerosis (MS) has advanced markedly over
the past few years. Technical improvements and continuously emerging data from clinical …

Objective Gray matter (GM) damage and meningeal inflammation have been associated
with early disease onset and a more aggressive disease course in multiple sclerosis (MS) …

Pathological evaluation is the gold standard for identifying processes related to multiple
sclerosis that explain disease manifestations, and for guiding the development of new …

MRI red flags proposed over a decade ago by the European Magnetic Resonance Network
in MS (MAGNIMS) have guided clinicians in the diagnosis of multiple sclerosis (MS) …